| Name |
TIAM Rac1 associated GEF 2 |
par-3 family cell polarity regulator |
| Structure |
No pdb structure
|
|
| GO Annotations |
Cellular Component |
|
|
| Molecular Function |
|
|
| Biological Process |
|
|
| Pathways |
|
|
| GWAS |
- Accelerated cognitive decline after conversion of mild cognitive impairment to Alzheimer's disease (Alzhiemer's diagnosis trajectory interaction) ( 28560309
)
- Appendicular lean mass ( 33097823
)
- Asthma ( 31361310
)
- Dimensional psychopathology (Arousal) ( 29496196
)
- Dimensional psychopathology (Negative) ( 29496196
)
- Femur bone mineral density x serum urate levels interaction ( 34046847
)
- Heel bone mineral density ( 30598549
)
- Lipoprotein (a) levels ( 26377243
)
- Triiodothyronine levels and thyroxine levels ( 30843173
)
|
- Acute lymphoblastic leukemia (childhood) ( 19684603
)
- Adult body size ( 32376654
)
- Apolipoprotein A1 levels ( 32203549
)
- Appendicular lean mass ( 33097823
)
- Brain morphology (MOSTest) ( 32665545
)
- Corneal astigmatism ( 30306274
)
- Emphysema-related traits ( 20709820
)
- Estimated glomerular filtration rate ( 31015462
)
- Gut microbiota relative abundance (Sutterella) ( 33208821
)
- HDL cholesterol levels ( 32203549
)
- Hip circumference adjusted for BMI ( 28552196
)
- Liver enzyme levels (gamma-glutamyl transferase) ( 33972514
)
- Lung function (FEV1/FVC) ( 30804560
)
- Major depressive disorder ( 21621269
)
- Parkinson's disease progression (composite) ( 33111402
)
- Schizophrenia ( 21682944
)
|
| Interacting Genes |
9 interacting genes:
ANXA7
DISC1
DNM2
H2AX
PARD3
SH3GL2
TK1
TNIK
UFD1
|
31 interacting genes:
ACE2
CDC42
DYNLL1
F11R
INSC
LIMK2
NECTIN1
NECTIN3
PARD6A
PARD6B
PARD6G
PATJ
PLCB1
PLCB3
PNMA1
PRKCG
PRKCI
SMAD1
SMAD2
SMAD3
SMAD4
SMAD7
STK11
TIAM1
TIAM2
TTN
UBC
YWHAB
YWHAG
YWHAH
YWHAZ
|
| Entrez ID |
26230 |
56288 |
| HPRD ID |
05273
|
05994
|
| Ensembl ID |
ENSG00000146426
|
ENSG00000148498
|
| Uniprot IDs |
B3KW11
Q8IVF5
|
Q8TEW0
|
| PDB IDs |
Not available
|
2KOM
|
| GO Terms Enriched among Interactors |
|
|