RAB11FIP5 and NAPG

Number of citations: 97 (PubMedID 33961781)
Data Source: BioGRID (affinity chromatography technology), HPRD (two hybrid, in vitro)

		RAB11FIP5	NAPG
Name		RAB11 family interacting protein 5	NSF attachment protein gamma
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endosome Early Endosome Golgi Apparatus Plasma Membrane Cilium Membrane Nuclear Speck Secretory Granule Transport Vesicle Membrane Cytoplasmic Vesicle Early Endosome Membrane Mitochondrial Membrane Centriolar Satellite Ciliary Basal Body Phagocytic Vesicle Recycling Endosome Recycling Endosome Membrane	Mitochondrion Lysosomal Membrane Golgi Apparatus Membrane SNARE Complex Extracellular Exosome
	Molecular Function	Protein Binding Small GTPase Binding Gamma-tubulin Binding	Soluble NSF Attachment Protein Activity Protein Binding Syntaxin Binding
	Biological Process	Protein Transport Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulated Exocytosis Negative Regulation Of Adiponectin Secretion Cellular Response To Acidic PH Regulation Of Protein Localization To Cell Surface	Intracellular Protein Transport Intra-Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport Protein Stabilization Membrane Fusion Protein-containing Complex Assembly
Pathways		None	COPII-mediated vesicle transport COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203 ) Estimated glomerular filtration rate ( 31152163 ) Non-word reading ( 30741946 ) Pediatric areal bone mineral density (spine vs radius & hip discordant skeletal phenotype) ( 29240982 ) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995 )	Gut microbiota (bacterial taxa) ( 27723756 ) Metabolite levels ( 23823483 ) Non-small cell lung cancer ( 21866343 )
Interacting Genes		10 interacting genes: ARF6 NAPG RAB11A RAB11B RAB11FIP4 RAB14 RAB25 RO60 TRIM21 YWHAG	5 interacting genes: APP NSF RAB11FIP5 STX8 TUBG1
Entrez ID		26056	8774
HPRD ID		16117	04448
Ensembl ID		ENSG00000135631	ENSG00000134265
Uniprot IDs		A0A1B0GTL5 Q9BXF6	Q6FHY4 Q99747
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Myosin V Binding G Protein Activity Endocytic Recycling Recycling Endosome Membrane Vesicle-mediated Transport To The Plasma Membrane Recycling Endosome Endosomal Transport Protein Localization To Cleavage Furrow GTPase Activity GTP Binding Vesicle-mediated Transport Positive Regulation Of Epithelial Cell Migration Cleavage Furrow Positive Regulation Of Mitotic Cytokinetic Process Establishment Of Protein Localization Golgi Apparatus Amyloid-beta Clearance By Transcytosis Cytoplasmic Vesicle Extracellular Exosome Regulation Of Epithelial Cell Migration GDP Binding Localization Within Membrane Phagocytic Vesicle Regulation Of Cytokinesis Positive Regulation Of Mitotic Cytokinesis Protein Transport Regulation Of Mitotic Cytokinesis Intracellular Protein Localization Positive Regulation Of Cell Cycle Intracellular Transport Transcytosis Regulation Of Endocytic Recycling Endosome Melanosome Transport Establishment Of Melanosome Localization Pigment Granule Transport Melanosome Localization Pigment Granule Localization Protein K6-linked Ubiquitination Amyloid-beta Clearance Protein Localization To Cell Surface Regulation Of Cell Division Regulation Of Protein Localization Cellular Localization Establishment Of Localization In Cell Regulation Of Protein Localization To Cell Surface Exocytosis Vesicle Docking Involved In Exocytosis Hydrolase Activity Intracellular Protein Transport	Recycling Endosome Amyloid-beta Complex Dendritic Shaft Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Early Endosome Vesicle-mediated Transport Syntaxin Binding SNARE Binding Transferase Activity, Transferring One-carbon Groups Thymidylate Synthase Activity Phagocytic Vesicle Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Endosome Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Establishment Of Localization In Cell Postsynaptic Specialization, Intracellular Component SNARE Complex Disassembly Membrane Fusion Polar Microtubule Microtubule Nucleator Activity DTMP Biosynthetic Process Pyrimidine Deoxyribonucleoside Monophosphate Biosynthetic Process DTTP Biosynthetic Process Negative Regulation Of Adiponectin Secretion Regulation Of Spontaneous Synaptic Transmission Early Endosome Membrane NMDA Selective Glutamate Receptor Signaling Pathway