RAB11FIP5 and RO60

Number of citations: 41 (PubMedID 10545525)
Data Source: HPRD (in vivo, two hybrid, in vitro)

		RAB11FIP5	RO60
Name		RAB11 family interacting protein 5	Ro60, Y RNA binding protein
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endosome Early Endosome Golgi Apparatus Plasma Membrane Cilium Membrane Nuclear Speck Secretory Granule Transport Vesicle Membrane Cytoplasmic Vesicle Early Endosome Membrane Mitochondrial Membrane Centriolar Satellite Ciliary Basal Body Phagocytic Vesicle Recycling Endosome Recycling Endosome Membrane	Nucleus Nucleoplasm Cytoplasm Cytosol Cilium Nuclear Body Ribonucleoprotein Complex
	Molecular Function	Protein Binding Small GTPase Binding Gamma-tubulin Binding	RNA Binding U2 SnRNA Binding Metal Ion Binding
	Biological Process	Protein Transport Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulated Exocytosis Negative Regulation Of Adiponectin Secretion Cellular Response To Acidic PH Regulation Of Protein Localization To Cell Surface	Immune System Development Transcription By RNA Polymerase III Smoothened Signaling Pathway Response To UV Regulation Of Gene Expression Cell Projection Organization Cellular Response To Interferon-alpha Cilium Assembly
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203 ) Estimated glomerular filtration rate ( 31152163 ) Non-word reading ( 30741946 ) Pediatric areal bone mineral density (spine vs radius & hip discordant skeletal phenotype) ( 29240982 ) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995 )	No GWAS studies recorded
Interacting Genes		10 interacting genes: ARF6 NAPG RAB11A RAB11B RAB11FIP4 RAB14 RAB25 RO60 TRIM21 YWHAG	8 interacting genes: CDC42 DDX6 FILNC1 OGT RAB11FIP5 RNY1 RNY3 TRIM21
Entrez ID		26056	6738
HPRD ID		16117	15964
Ensembl ID		ENSG00000135631	ENSG00000116747
Uniprot IDs		A0A1B0GTL5 Q9BXF6	G5E9R9 P10155
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Myosin V Binding G Protein Activity Endocytic Recycling Recycling Endosome Membrane Vesicle-mediated Transport To The Plasma Membrane Recycling Endosome Endosomal Transport Protein Localization To Cleavage Furrow GTPase Activity GTP Binding Vesicle-mediated Transport Positive Regulation Of Epithelial Cell Migration Cleavage Furrow Positive Regulation Of Mitotic Cytokinetic Process Establishment Of Protein Localization Golgi Apparatus Amyloid-beta Clearance By Transcytosis Cytoplasmic Vesicle Extracellular Exosome Regulation Of Epithelial Cell Migration GDP Binding Localization Within Membrane Phagocytic Vesicle Regulation Of Cytokinesis Positive Regulation Of Mitotic Cytokinesis Protein Transport Regulation Of Mitotic Cytokinesis Intracellular Protein Localization Positive Regulation Of Cell Cycle Intracellular Transport Transcytosis Regulation Of Endocytic Recycling Endosome Melanosome Transport Establishment Of Melanosome Localization Pigment Granule Transport Melanosome Localization Pigment Granule Localization Protein K6-linked Ubiquitination Amyloid-beta Clearance Protein Localization To Cell Surface Regulation Of Cell Division Regulation Of Protein Localization Cellular Localization Establishment Of Localization In Cell Regulation Of Protein Localization To Cell Surface Exocytosis Vesicle Docking Involved In Exocytosis Hydrolase Activity Intracellular Protein Transport	None