GEMIN5 and RN7SL1

Number of citations: 111 (PubMedID 23221635)
Data Source: BioGRID (unspecified method)

		GEMIN5	RN7SL1
Name		gem nuclear organelle associated protein 5	RNA component of signal recognition particle 7SL1
Structure			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Body SMN Complex SMN-Gemin2 Complex SMN-Sm Protein Complex Gemini Of Cajal Bodies	Signal Recognition Particle, Endoplasmic Reticulum Targeting
	Molecular Function	RNA 7-methylguanosine Cap Binding RNA Binding MRNA 3'-UTR Binding Protein Binding SnRNA Binding U1 SnRNA Binding U4 SnRNA Binding U4atac SnRNA Binding Ribosome Binding	None
	Biological Process	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome MRNA Processing Translation Regulation Of Translation RNA Splicing Protein-containing Complex Assembly	SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition
Pathways		snRNP Assembly SARS-CoV-2 modulates host translation machinery	None
GWAS		Venous thromboembolism ( 32232851 )	No GWAS studies recorded
Interacting Genes		22 interacting genes: CLK1 DDX20 EIF4E GEMIN2 GEMIN4 MAP2K4 MAP3K5 MAPK8 RN7SL1 RNF10 RNU1-1 RNU2-1 SMN1 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG STXBP3 SUMO2	9 interacting genes: DDX20 GEMIN2 GEMIN4 GEMIN5 GEMIN6 GEMIN7 GEMIN8 SMN1 STRAP
Entrez ID		25929	6029
HPRD ID		06109	Not available
Ensembl ID		ENSG00000082516	ENSG00000276168
Uniprot IDs		B7ZLC9 Q58EZ8 Q8TEQ6	Not available
PDB IDs		5GXH 5GXI 5H1J 5H1K 5H1L 5H1M 5H3S 5H3T 5H3U 5TEE 5TEF 5THA 6RNQ 6RNS 7XDT 7XGR	Not available
GO Terms Enriched among Interactors		SMN-Sm Protein Complex Spliceosomal SnRNP Assembly 7-methylguanosine Cap Hypermethylation Small Nuclear Ribonucleoprotein Complex U4 SnRNP Methylosome Spliceosomal Complex Assembly U2 SnRNP Protein-RNA Complex Assembly U1 SnRNP U5 SnRNP U2-type Prespliceosome Assembly U12-type Spliceosomal Complex U2-type Spliceosomal Complex U2-type Catalytic Step 2 Spliceosome PICln-Sm Protein Complex U7 SnRNP U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome RNA Splicing MRNA Processing RNA Splicing, Via Transesterification Reactions RNA Methylation Catalytic Step 2 Spliceosome Precatalytic Spliceosome Spliceosomal Complex Protein-containing Complex Assembly Macromolecule Methylation MRNA Metabolic Process Protein-containing Complex Organization SMN Complex Gemini Of Cajal Bodies RNA Modification RNA Processing MRNA Splicing, Via Spliceosome Methylation Spliceosomal Tri-snRNP Complex Cellular Component Assembly Ribonucleoprotein Complex RNA Metabolic Process Telomerase Holoenzyme Complex Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Nuclear Body Histone Pre-mRNA DCP Binding RNA Binding Commitment Complex U1 SnRNP Binding JNK Cascade Cytosol	SMN Complex SMN-Sm Protein Complex Gemini Of Cajal Bodies Spliceosomal SnRNP Assembly Protein-RNA Complex Assembly RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing Protein-containing Complex Assembly Nuclear Body RNA Metabolic Process Protein-containing Complex Organization RNA Splicing, Via Transesterification Reactions Nucleic Acid Metabolic Process Cellular Component Assembly Nucleobase-containing Compound Metabolic Process Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome Macromolecule Metabolic Process Cytosol Nucleoplasm Nucleus Cytoplasm RNA Binding Cajal Body SMN-Gemin2 Complex Sm-like Protein Family Complex U2 SnRNP Binding U4atac SnRNA Binding U4 SnRNA Binding RNA Polymerase II Transcription Repressor Complex U1 SnRNA Binding SnRNA Binding Ribonucleoside Triphosphate Phosphatase Activity RNA 7-methylguanosine Cap Binding MRNA Binding Small Nuclear Ribonucleoprotein Complex Spliceosomal Tri-snRNP Complex Assembly DNA-templated Transcription Termination Maintenance Of Gastrointestinal Epithelium Alternative MRNA Splicing, Via Spliceosome