FTL and CLEC4G

Number of citations: 0 (PubMedID 18624398)
Data Source: BioGRID (two hybrid)

		FTL	CLEC4G
Name		ferritin light chain	C-type lectin domain family 4 member G
Structure			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Lysosome Autophagosome Cytosol Membrane Cytoplasmic Vesicle Azurophil Granule Lumen Autolysosome Extracellular Exosome Ferritin Complex	Plasma Membrane External Side Of Plasma Membrane Membrane
	Molecular Function	Iron Ion Binding Protein Binding Ferrous Iron Binding Ferric Iron Binding Identical Protein Binding Metal Ion Binding	Virus Receptor Activity Protein Binding D-mannose Binding Carbohydrate Binding Polysaccharide Binding Pattern Recognition Receptor Activity Fructose Binding Carbohydrate Derivative Binding Virus Coreceptor Activity Glycosylated Region Protein Binding
	Biological Process	Iron Ion Transport Intracellular Iron Ion Homeostasis	T Cell Mediated Immunity Negative Regulation Of T Cell Mediated Immunity Immune Response Immature T Cell Proliferation In Thymus Negative Regulation Of Immature T Cell Proliferation In Thymus Negative Regulation Of T Cell Proliferation Alpha-beta T Cell Proliferation Negative Regulation Of Alpha-beta T Cell Proliferation Symbiont Entry Into Host Cell Positive Regulation Of Viral Life Cycle
Pathways		Scavenging by Class A Receptors Golgi Associated Vesicle Biogenesis Neutrophil degranulation Iron uptake and transport	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs		Iron Dextran Protoporphyrin Ferric pyrophosphate Sodium ferric gluconate complex Ferric pyrophosphate citrate	None
Diseases		Neurodegeneration with brain iron accumulation (NBIA); Hallervorden-Spatz syndrome; Neuroferritinopathy; Aceruloplasminemia	None
GWAS		No GWAS studies recorded	Post bronchodilator FEV1 ( 26634245 )
Interacting Genes		31 interacting genes: ACO1 CLEC4G FTH1 GADD45A GLP1R GRB2 HTT IGDCC3 KNG1 KPNA3 MAP3K12 MEOX2 MPHOSPH6 MTNR1B MYOC MYOG NTAQ1 PALS2 PIK3CA PPP1CC PTN RAP2A SDCBP SLC13A1 SMAD9 SPINK7 TAF10 UBC USHBP1 VKORC1 ZDHHC17	27 interacting genes: APOA1 APOH ARL13B ARSA ASGR1 AZU1 CAPN1 CPLX4 CPN1 EBAG9 EIF6 FAM209A FTL GEM IFI35 LRRC4C MAP3K11 MT-CO1 NUP214 PKLR PRDX1 PTPN5 RPSA SHBG SIGLEC12 TNFAIP3 WBP2
Entrez ID		2512	339390
HPRD ID		00616	16721
Ensembl ID		ENSG00000087086	ENSG00000182566
Uniprot IDs		A0A384MDR3 P02792	B7ZKQ2 Q08G24 Q6UXB4 Q6XYD1
PDB IDs		2FFX 2FG4 2FG8 3KXU 4V6B 5LG8 6TR9 6TS0 6TS1 6TSA 6TSF 6TSJ 6WX6	Not available
GO Terms Enriched among Interactors		None	Extracellular Exosome