ATP6V0D2 and RBM15B

Number of citations: 38 (PubMedID 21988832)
Data Source: BioGRID (two hybrid)

		ATP6V0D2	RBM15B
Name		ATPase H+ transporting V0 subunit d2	RNA binding motif protein 15B
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Endosome Early Endosome Endosome Membrane Membrane Apical Plasma Membrane Vacuolar Proton-transporting V-type ATPase Complex Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain Plasma Membrane Proton-transporting V-type ATPase Complex Extracellular Exosome	Nucleus Nuclear Envelope Nucleoplasm Nucleolus Nuclear Speck RNA N6-methyladenosine Methyltransferase Complex
	Molecular Function	Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	Monoatomic Ion Transport Vacuolar Transport Vacuolar Acidification Regulation Of Macroautophagy Proton Transmembrane Transport	Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Methylation MRNA Processing MRNA Export From Nucleus Nucleocytoplasmic Transport RNA Splicing Dosage Compensation By Inactivation Of X Chromosome Negative Regulation Of DNA-templated Transcription
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport	None
Drugs		Tiludronic acid	None
GWAS		Adverse response to lamotrigine and phenytoin ( 22379998 ) Neutrophil count ( 32888494 )	Allergic disease (asthma, hay fever or eczema) ( 29679657 ) Lipoprotein (a) levels ( 33730874 )
Interacting Genes		20 interacting genes: ADRM1 AGO3 ARID5A CENPP CRX IKZF3 INCA1 MEOX2 NDUFB8 NICN1 PAX6 PHF12 POMC RBM15B REL RIBC1 RPS3 RUSC1 SEPTIN2 ZNF474	11 interacting genes: ATP6V0D2 CDC23 DVL3 EGR2 ERBB2 NAV2 NXF1 RNF10 SRPK2 TNNC1 TRIM54
Entrez ID		245972	29890
HPRD ID		16522	11486
Ensembl ID		ENSG00000147614	ENSG00000259956
Uniprot IDs		Q8N8Y2	Q8NDT2
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		NF-kappaB Complex DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Nucleus Nucleoplasm Sequence-specific DNA Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II	Motor Neuron Axon Guidance Peripheral Nervous System Development Regulation Of Nervous System Process Positive Regulation Of Myelination Rhythmic Behavior Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Rhombomere 5 Structural Organization Rhombomere 3 Structural Organization Rhombomere 3 Formation Rhombomere 5 Formation Regulation Of Myelination Negative Regulation Of Synaptic Vesicle Clustering Regulation Of Muscle Filament Sliding Speed Glossopharyngeal Nerve Development Regulation Of Systemic Arterial Blood Pressure By Baroreceptor Feedback Vagus Nerve Development