CDK20 and PANK4

Number of citations: 36 (PubMedID 18508765)
Data Source: BioGRID (two hybrid)

		CDK20	PANK4
Name		cyclin dependent kinase 20	pantothenate kinase 4 (inactive)
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cilium Cell Projection	Nucleus Cytoplasm Cytosol
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity	Nucleotide Binding Pantothenate Kinase Activity ATP Binding Hydrolase Activity Phosphatase Activity Metal Ion Binding
	Biological Process	Neural Tube Closure Regulation Of Smoothened Signaling Pathway Floor Plate Formation Embryonic Camera-type Eye Development Negative Regulation Of Smoothened Signaling Pathway Embryonic Skeletal System Development Cell Division Regulation Of Cell Cycle Roof Of Mouth Development Protein Localization To Cilium Regulation Of Protein Maturation Embryonic Brain Development	Coenzyme A Biosynthetic Process Pantothenate Metabolic Process
Pathways		None	Vitamin B5 (pantothenate) metabolism
GWAS		No GWAS studies recorded	Obesity-related traits ( 23251661 )
Interacting Genes		9 interacting genes: CCNH CDK2 CILK1 CSNK2B GTF2IRD1 GTF2IRD2 PANK4 PPP5C TRIM2	2 interacting genes: CDK20 PEA15
Entrez ID		23552	55229
HPRD ID		13010	07313
Ensembl ID		ENSG00000156345	ENSG00000157881
Uniprot IDs		A0A0S2Z562 A0A0S2Z5B6 Q8IZL9	Q9NVE7
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Phosphate-containing Compound Metabolic Process Phosphorylation Protein Phosphorylation DNA-templated Transcription Nucleobase-containing Compound Biosynthetic Process Protein Modification Process Kinase Activity Cyclin-dependent Protein Kinase Holoenzyme Complex Male Germ Cell Nucleus ATP Binding Brain-derived Neurotrophic Factor Receptor Activity Transition Between Slow And Fast Fiber Macromolecule Metabolic Process Y Chromosome Positive Regulation Of Heterochromatin Formation Cyclin A1-CDK2 Complex Cyclin E2-CDK2 Complex Positive Regulation Of DNA-templated DNA Replication Initiation Positive Regulation Of Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Phosphatase Activity Pantothenate Kinase Activity Transcription Factor TFIIK Complex Positive Regulation Of Chromatin Organization Protein Serine/threonine Kinase Activity Cyclin-dependent Protein Kinase Activity Cyclin A2-CDK2 Complex Cyclin E1-CDK2 Complex Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Trans-synaptic Signaling By BDNF, Modulating Synaptic Transmission Brain-derived Neurotrophic Factor Binding Response To Arachidonate Peptidyl-serine Dephosphorylation CAK-ERCC2 Complex X Chromosome Brain-derived Neurotrophic Factor Receptor Signaling Pathway Neurotrophin Receptor Activity Trans-synaptic Signaling By BDNF Neurotrophin Binding Protein Kinase Activity Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Metabolic Process Release From Viral Latency Pantothenate Metabolic Process Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Histone Kinase Activity Positive Regulation Of Activin Receptor Signaling Pathway Negative Regulation Of Viral Life Cycle Regulation Of G1/S Transition Of Mitotic Cell Cycle Protection From Non-homologous End Joining At Telomere	Floor Plate Formation Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Signal Transduction Negative Regulation Of D-glucose Import Negative Regulation Of Cell Communication Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Microtubule Associated Complex Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of D-glucose Import Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Signaling Regulation Of D-glucose Transmembrane Transport Negative Regulation Of D-glucose Transmembrane Transport Tube Closure Regulation Of Smoothened Signaling Pathway Protein Localization To Cilium Embryonic Skeletal System Development Regulation Of Protein Maturation Neural Tube Closure Camera-type Eye Development Negative Regulation Of Smoothened Signaling Pathway Roof Of Mouth Development Cyclin-dependent Protein Serine/threonine Kinase Activity Embryonic Brain Development Embryonic Camera-type Eye Development Negative Regulation Of Extrinsic Apoptotic Signaling Pathway