SLC16A8 and RAB1A

Number of citations: 0 (PubMedID 16169070)
Data Source: BioGRID (two hybrid), HPRD (two hybrid)

		SLC16A8	RAB1A
Name		solute carrier family 16 member 8	RAB1A, member RAS oncogene family
Structure		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Apical Part Of Cell	Golgi Membrane Cytoplasm Endosome Early Endosome Endoplasmic Reticulum Golgi Apparatus Cytosol Endomembrane System Membrane Transport Vesicle Membrane Melanosome Extracellular Exosome
	Molecular Function	Monocarboxylic Acid Transmembrane Transporter Activity Lactate Transmembrane Transporter Activity Symporter Activity Transmembrane Transporter Activity	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity Cadherin Binding Metal Ion Binding
	Biological Process	Monocarboxylic Acid Transport Lactate Transport Lactate Transmembrane Transport Transmembrane Transport	Autophagosome Assembly Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endocytosis Autophagy Golgi Organization Protein Transport Vesicle-mediated Transport Cell Migration Virion Assembly Growth Hormone Secretion Melanosome Transport Positive Regulation Of Interleukin-8 Production Substrate Adhesion-dependent Cell Spreading Defense Response To Bacterium Vesicle Transport Along Microtubule Cilium Assembly COPII-coated Vesicle Cargo Loading Establishment Of Endothelial Intestinal Barrier Positive Regulation Of Glycoprotein Metabolic Process
Pathways		Basigin interactions Proton-coupled monocarboxylate transport	Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs		Pyruvic acid	None
GWAS		Advanced age-related macular degeneration ( 26691988 ) Age-related macular degeneration ( 23455636 ) Brain morphology (MOSTest) ( 32665545 ) Glioblastoma ( 28346443 ) Glioma ( 28346443 )	High light scatter reticulocyte percentage of red cells ( 32888494 ) Reticulocyte count ( 32888494 ) Triglyceride levels ( 32154731 )
Interacting Genes		2 interacting genes: DNAJB9 RAB1A	32 interacting genes: ADCK1 CAPNS1 CDKN1A CHML CREB1 CSNK1D FNDC3B FSCN1 GOLGA2 GOLGA5 GORASP2 HIVEP1 MAPRE3 MICAL1 MICALL1 MTOR OCRL PLK1 PSMD7 RABAC1 RABEP1 RABGGTA RABGGTB RFK RUSC2 SLC16A8 SNCA SSX2IP SYT5 TBC1D17 USO1 ZNF593
Entrez ID		23539	5861
HPRD ID		11568	01538
Ensembl ID		ENSG00000100156	ENSG00000138069
Uniprot IDs		O95907	B7Z8M7 P62820 Q5U0I6
PDB IDs		Not available	2FOL 2WWX 3L0I 3SFV 3TKL 4FMB 4FMC 4FMD 4FME 4IRU 4JVS 7EQ2 9MHF 9MHG 9MHH
GO Terms Enriched among Interactors		Regulation Of IRE1-mediated Unfolded Protein Response Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Misfolded Protein Binding Negative Regulation Of IRE1-mediated Unfolded Protein Response Positive Regulation Of Glycoprotein Metabolic Process Pigment Granule Localization Establishment Of Melanosome Localization Establishment Of Endothelial Intestinal Barrier Melanosome Localization COPII-coated Vesicle Cargo Loading Melanosome Transport Pigment Granule Transport Growth Hormone Secretion Virion Assembly Vesicle Cargo Loading Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Gene Expression Hsp70 Protein Binding Negative Regulation Of Response To Endoplasmic Reticulum Stress Vesicle Transport Along Microtubule Substrate Adhesion-dependent Cell Spreading Endothelial Cell Development Establishment Of Endothelial Barrier Transport Vesicle Membrane	Rab-protein Geranylgeranyltransferase Complex Protein Geranylgeranylation Small GTPase Binding Golgi Organization Protein Prenylation Vesicle-mediated Transport Organelle Organization Golgi Vesicle Transport Rab Geranylgeranyltransferase Activity Protein Geranylgeranyltransferase Activity Protein Prenyltransferase Activity Cytoplasm Organelle Assembly Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Cellular Localization Protein Localization To Cytoskeleton Centrosome Cycle Cis-Golgi Network Establishment Of Localization In Cell Prenyltransferase Activity Protein Destabilization Cytoplasmic Vesicle Protein Localization To Cilium Spindle Organization Cytosol Ciliary Basal Body Cadherin Binding Intracellular Transport Behavioral Response To Cocaine Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Microtubule Organizing Center Organization Positive Regulation Of Protein-containing Complex Assembly Plasma Membrane Bounded Cell Projection Assembly Positive Regulation Of Vesicle Fusion Establishment Of Protein Localization Cell Projection Assembly Spindle Assembly Protein Serine/threonine Kinase Binding Protein Localization To Organelle GTPase Activator Activity Chemotaxis To Arachidonate Regulation Of Protein-containing Complex Assembly Microtubule Nucleation Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Cilium Assembly Cellular Component Assembly Protein Localization To Centrosome Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Lamellipodium Assembly Regulation Of Organelle Assembly