NOMO1 and SHBG

Number of citations: 0 (PubMedID 15862967)
Data Source: HPRD (two hybrid)

		NOMO1	SHBG
Name		NODAL modulator 1	sex hormone binding globulin
Structure		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Multi-pass Translocon Complex	Extracellular Region Extracellular Exosome
	Molecular Function	Protein Binding Carbohydrate Binding Ribosome Binding	Steroid Binding Androgen Binding Protein Binding Lipid Binding
	Biological Process	Determination Of Left/right Asymmetry In Lateral Mesoderm Multi-pass Transmembrane Protein Insertion Into ER Membrane Negative Regulation Of Nodal Signaling Pathway	None
Drugs		Theophylline	Masoprocol Diethylstilbestrol Levonorgestrel Progesterone Spironolactone Toremifene Estrone Tamoxifen Clomifene Dienestrol Hesperetin Zinc Genistein Naringenin Quercetin 4'-Hydroxyflavanone Afimoxifene Estriol Phenolphthalein Norethynodrel Dioxybenzone Zeranol Gestrinone Equol Zinc acetate Zinc chloride Zinc sulfate, unspecified form Estriol tripropionate
GWAS		No GWAS studies recorded	A body shape index ( 34021172 ) Androgen levels ( 22936694 ) Body size at age 10 ( 32376654 ) Brain morphology (MOSTest) ( 32665545 ) Estradiol levels ( 34255042 ) Glycated hemoglobin levels ( 34059833 ) Heel bone mineral density ( 30598549 ) Hormone measurements ( 24049095 ) Medication use (calcium channel blockers) ( 31015401 ) Protein quantitative trait loci ( 18464913 ) Red cell distribution width ( 27863252 ) Refractive error ( 32231278 ) Sex hormone levels ( 26014426 ) Sex hormone-binding globulin levels ( 22675492 22829776 ) Testosterone levels ( 21998597 ) Uterine fibroids ( 31649266 ) Waist circumference adjusted for body mass index ( 34021172 ) Waist-hip index ( 34021172 ) Waist-to-hip ratio adjusted for BMI ( 34021172 )
Interacting Genes		13 interacting genes: ATF7IP BAG6 DLG4 ECT2 EXOSC10 NCLN SHBG STAT1 TOM1L1 TRIM55 TRIM63 UBQLN4 UPF2	62 interacting genes: A2M ACP3 ACTA2 ACTB ACTG2 AK2 AKR1B1 AP1B1 AP2A1 APEH APOBEC3C APOD ASB16-AS1 ATP5F1A AZGP1 CD177 CEP192 CLDN4 CLEC4G COL1A2 CTSD DDX3Y DES DSTN EEF1A1 EIF3E EIF3F FLNA FLOT1 FYTTD1 GRB2 HDHD5 HYI JMJD7-PLA2G4B KLK4 MPDU1 MT1F MT1G MT2A MXD4 NOMO1 PACSIN2 PKM PLA2G4A PLP2 PSTPIP1 PSTPIP2 PTGDS RMND5B SEMA3F SLC37A1 SLC37A4 SNAPIN SNRNP70 SORD SPMIP6 SRF SRI TINAGL1 UBE2O UBE3A ZC3H12A
Entrez ID		23420	6462
HPRD ID		11398	01646
Ensembl ID		ENSG00000103512	ENSG00000129214
Uniprot IDs		Q15155	B0FWH2 B0FWH8 I3L145 P04278
PDB IDs		Not available	1D2S 1F5F 1KDK 1KDM 1LHN 1LHO 1LHU 1LHV 1LHW 6PYA 6PYB 6PYF 6ULB
GO Terms Enriched among Interactors		None	Extracellular Exosome Protease Binding Cell-cell Junction Fructose Biosynthetic Process Detoxification Of Copper Ion Extracellular Space Glucose 6-phosphate:phosphate Antiporter Activity Cellular Response To Cadmium Ion Lamellipodium Cellular Response To Zinc Ion Cellular Response To Copper Ion Mesenchyme Migration Glucose-6-phosphate Transport Negative Regulation Of Cardiac Muscle Contraction Intracellular Zinc Ion Homeostasis Prostaglandin Metabolic Process Prostanoid Metabolic Process Response To Copper Ion Rough Endoplasmic Reticulum Hexose Metabolic Process Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Striated Muscle Contraction Response To Cadmium Ion Cell-cell Junction Organization Caveola Assembly Carbohydrate Metabolic Process Monosaccharide Metabolic Process Plasma Membrane Raft Assembly Response To Zinc Ion