NOMO1 and NCLN

Number of citations: 64 (PubMedID 15257293)
Data Source: BioGRID (cross-linking study, cross-linking study), HPRD (in vivo, in vitro)

		NOMO1	NCLN
Name		NODAL modulator 1	nicalin
Structure		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Multi-pass Translocon Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Protein-containing Complex Multi-pass Translocon Complex
	Molecular Function	Protein Binding Carbohydrate Binding Ribosome Binding	Protein Binding Ribosome Binding
	Biological Process	Determination Of Left/right Asymmetry In Lateral Mesoderm Multi-pass Transmembrane Protein Insertion Into ER Membrane Negative Regulation Of Nodal Signaling Pathway	Determination Of Left/right Asymmetry In Lateral Mesoderm Regulation Of Signal Transduction Regulation Of Protein-containing Complex Assembly Protein Stabilization Regulation Of Protein Complex Stability Multi-pass Transmembrane Protein Insertion Into ER Membrane Negative Regulation Of Nodal Signaling Pathway
Drugs		Theophylline	None
GWAS		No GWAS studies recorded	Asthma ( 31959851 ) Basophil percentage of white cells ( 32888494 ) Height ( 31562340 ) Lymphocyte percentage of white cells ( 32888494 ) Neutrophil count ( 29403010 32888494 ) Neutrophil percentage of white cells ( 32888494 )
Interacting Genes		13 interacting genes: ATF7IP BAG6 DLG4 ECT2 EXOSC10 NCLN SHBG STAT1 TOM1L1 TRIM55 TRIM63 UBQLN4 UPF2	3 interacting genes: KRTAP5-9 NOMO1 NOMO3
Entrez ID		23420	56926
HPRD ID		11398	07126
Ensembl ID		ENSG00000103512	ENSG00000125912
Uniprot IDs		Q15155	Q969V3
PDB IDs		Not available	6W6L 9C7U 9C7V
GO Terms Enriched among Interactors		None	Negative Regulation Of Nodal Signaling Pathway Regulation Of Nodal Signaling Pathway Multi-pass Transmembrane Protein Insertion Into ER Membrane Multi-pass Translocon Complex Determination Of Left/right Asymmetry In Lateral Mesoderm Negative Regulation Of Activin Receptor Signaling Pathway Regulation Of Activin Receptor Signaling Pathway Protein Insertion Into ER Membrane Protein Insertion Into Membrane Ribosome Binding Determination Of Bilateral Symmetry Determination Of Left/right Symmetry Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Carbohydrate Binding Establishment Of Protein Localization To Membrane Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Pattern Specification Process Localization Within Membrane Endoplasmic Reticulum Membrane Establishment Of Protein Localization Negative Regulation Of Signal Transduction Cellular Localization Negative Regulation Of Cell Communication Endoplasmic Reticulum Negative Regulation Of Signaling Epidermis Development