DNAJC13 and DNAJB11

Number of citations: 0 (PubMedID 21900206)
Data Source: BioGRID (two hybrid)

		DNAJC13	DNAJB11
Name		DnaJ heat shock protein family (Hsp40) member C13	DnaJ heat shock protein family (Hsp40) member B11
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Endosome Early Endosome Cytosol Plasma Membrane Endosome Membrane Membrane Secretory Granule Membrane Early Endosome Membrane Azurophil Granule Membrane Extracellular Exosome WASH Complex	Extracellular Space Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Membrane Endoplasmic Reticulum Chaperone Complex Protein Folding Chaperone Complex
	Molecular Function	Protein Binding	Signaling Receptor Binding Protein Binding Unfolded Protein Binding Misfolded Protein Binding
	Biological Process	Osteoblast Differentiation Receptor-mediated Endocytosis Endosome Organization Protein Transport Regulation Of Early Endosome To Recycling Endosome Transport Regulation Of Early Endosome To Late Endosome Transport	Protein Folding MRNA Modification Positive Regulation Of ATP-dependent Activity Negative Regulation Of Neurogenesis Protein Maturation
Pathways		Neutrophil degranulation	XBP1(S) activates chaperone genes
GWAS		Apolipoprotein B levels ( 32203549 ) Appendicular lean mass ( 33097823 ) Aspartate aminotransferase levels ( 33547301 ) Body mass index ( 26426971 ) Brain morphology (min-P) ( 32665545 ) Brain morphology (MOSTest) ( 32665545 ) Coronary artery disease ( 29212778 ) Cortical surface area (MOSTest) ( 32665545 ) Hematocrit ( 32888494 ) Hemoglobin ( 32888494 ) Hemoglobin levels ( 32327693 ) Iron status biomarkers (total iron binding capacity) ( 28334935 ) Iron status biomarkers (transferrin saturation) ( 28334935 ) LDL cholesterol ( 30275531 ) LDL cholesterol levels ( 32203549 ) Liver enzyme levels (alkaline phosphatase) ( 33972514 ) Low density lipoprotein cholesterol levels ( 32154731 ) Mean corpuscular hemoglobin ( 32888494 ) Mean corpuscular hemoglobin concentration ( 32888494 ) Mean corpuscular volume ( 32888494 ) Neutrophil count ( 32888494 ) Red cell distribution width ( 32888494 28957414 27863252 ) Refractive error ( 32231278 ) Subcortical volume (MOSTest) ( 32665545 ) Total cholesterol levels ( 30275531 ) Urate levels ( 31578528 ) White blood cell count ( 32888494 )	No GWAS studies recorded
Interacting Genes		7 interacting genes: CALM1 CLK1 DNAJB11 GADD45A GSK3B RNF26 RPS6KA6	24 interacting genes: ANKZF1 APOBEC1 BAG6 CEP70 COL6A1 CRMP1 DDAH2 DNAJC13 DRAP1 EIF3D EZH2 FAF1 GRB2 HSPA1A HTN3 PAXIP1 PTN SIMC1 SNX5 SPRED1 SUMO4 UBQLN4 UBR1 ZZZ3
Entrez ID		23317	51726
HPRD ID		10915	07485
Ensembl ID		ENSG00000138246	ENSG00000090520
Uniprot IDs		B3KN02 O75165	Q9UBS4
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Negative Regulation Of Developmental Process Regulation Of Multicellular Organismal Process Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Calcium-mediated Signaling Protein Serine/threonine Kinase Activity Protein Serine Kinase Activity Negative Regulation Of Peptidyl-serine Phosphorylation Of STAT Protein Superior Temporal Gyrus Development TOR Signaling Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Mesenchymal Stem Cell Differentiation Negative Regulation Of Glycogen (starch) Synthase Activity Regulation Of Microtubule Anchoring At Centrosome Determination Of Stomach Left/right Asymmetry Determination Of Intestine Left/right Asymmetry Negative Regulation Of Embryonic Development Mitotic Cell Cycle Phase Transition Mitochondrion-endoplasmic Reticulum Membrane Tethering Positive Regulation Of Sequestering Of Calcium Ion Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Transporter Inhibitor Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Autophagosome Membrane Docking Cell Cycle Phase Transition Kinase Activity Protein Kinase Activity Negative Regulation Of Catalytic Activity Negative Regulation Of Peptidyl-serine Phosphorylation Signal Transduction In Response To DNA Damage Negative Regulation Of Multicellular Organismal Process Regulation Of Developmental Process Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Positive Regulation Of Protein Localization To Cilium Negative Regulation Of TORC2 Signaling Negative Regulation Of Cell Differentiation Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Dopaminergic Neuron Differentiation Cellular Response To Interleukin-3 Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of Protein Localization To Centrosome Maintenance Of Animal Organ Identity Ureter Development Ciliary Inversin Compartment Determination Of Digestive Tract Left/right Asymmetry	Cellular Response To Stress Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Oxidative Stress Positive Regulation Of Dendrite Development Regulation Of Proteasomal Protein Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process Cellular Response To Oxidative Stress Misfolded Protein Binding Biomineral Tissue Development Response To Endoplasmic Reticulum Stress ERAD Pathway