PEG10 and RTL8B

Number of citations: 97 (PubMedID 33961781)
Data Source: BioGRID (two hybrid, affinity chromatography technology)

		PEG10	RTL8B
Name		paternally expressed 10	retrotransposon Gag like 8B
Structure			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Extracellular Vesicle	None
	Molecular Function	Nucleic Acid Binding DNA Binding RNA Binding MRNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding
	Biological Process	Apoptotic Process Cell Differentiation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway MRNA Transport Protein Homooligomerization Viral Translational Frameshifting Vesicle-mediated Intercellular Transport	None
GWAS		No GWAS studies recorded	No GWAS studies recorded
Interacting Genes		21 interacting genes: CALCOCO2 CLIP4 EXOSC5 LAMTOR5 LNX2 MAPT NXF1 RAB3IP RBFOX2 RNF181 RTL8A RTL8B SIAH1 SIAH2 SMCHD1 SNRPA SNW1 TOLLIP UBC VPS26C ZNF512B	11 interacting genes: ALAS1 CCDC102B KRT13 PEG10 RIN3 SDCBP SPG21 TADA2A UBC UBQLN1 UBQLN2
Entrez ID		23089	441518
HPRD ID		15117	19134
Ensembl ID		ENSG00000242265	ENSG00000212747
Uniprot IDs		A0A087WZG9 Q86TG7	Q17RB0
PDB IDs		7LGA	Not available
GO Terms Enriched among Interactors		Amyloid Fibril Formation Ubiquitin Conjugating Enzyme Binding	Negative Regulation Of Receptor Internalization Negative Regulation Of Receptor-mediated Endocytosis Negative Regulation Of Endocytosis Regulation Of Receptor Internalization Regulation Of Receptor-mediated Endocytosis Positive Regulation Of ERAD Pathway Negative Regulation Of Transport Regulation Of ERAD Pathway Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Interleukin-5 Receptor Complex Negative Regulation Of Store-operated Calcium Channel Activity Negative Regulation Of Mast Cell Chemotaxis Cytosol Regulation Of Endocytosis 5-aminolevulinate Synthase Activity Response To Nickel Cation Interleukin-5 Receptor Binding Autophagosome Negative Regulation Of G Protein-coupled Receptor Internalization Extracellular Vesicle Regulation Of Response To Endoplasmic Reticulum Stress Autophagosome Assembly ERAD Pathway Vesicle-mediated Intercellular Transport Autophagosome Organization Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Response To Platinum Ion Positive Regulation Of Extracellular Exosome Assembly Syndecan Binding Negative Regulation Of Clathrin-dependent Endocytosis Positive Regulation Of Proteasomal Protein Catabolic Process Response To Herbicide Positive Regulation Of Proteolysis Involved In Protein Catabolic Process