COPZ1 and TMED9

Number of citations: 69 (PubMedID 9472029)
Data Source: BioGRID (unspecified method)

		COPZ1	TMED9
Name		coat protein complex I subunit zeta 1	transmembrane p24 trafficking protein 9
Structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane Membrane Coat COPI Vesicle Coat Transport Vesicle COPI-coated Vesicle Membrane Cytoplasmic Vesicle	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Synaptic Vesicle Membrane Transport Vesicle COPII-coated ER To Golgi Transport Vesicle Trans-Golgi Network Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Extracellular Exosome
	Molecular Function	None	Protein Binding Syntaxin Binding
	Biological Process	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Positive Regulation Of Organelle Organization Protein Transport Protein Exit From Endoplasmic Reticulum Early Endosome To Golgi Transport COPI Coating Of Golgi Vesicle
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
GWAS		Chronotype ( 30696823 ) Hematocrit ( 32888494 ) High light scatter reticulocyte percentage of red cells ( 32888494 ) Mean platelet volume ( 22139419 24026423 27863252 32888494 ) Meat-related diet ( 32066663 ) Platelet count ( 23263863 32888494 29403010 ) Platelet distribution width ( 32888494 ) Plateletcrit ( 32888494 ) Red blood cell count ( 27863252 32888494 ) Red cell distribution width ( 27863252 32888494 ) Refractive error ( 32231278 ) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971 )	Obesity-related traits ( 23251661 ) Waist-to-hip ratio adjusted for BMI ( 26426971 ) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971 ) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971 )
Interacting Genes		6 interacting genes: APP COPG1 COPG2 TMED10 TMED9 UGT1A1	14 interacting genes: AQP9 CDC42 CKMT2 COPZ1 DDX54 ITM2A MTF2 NMT2 PLPPR2 SEC22A SEC23B THAP8 TMEM60 YTHDF1
Entrez ID		22818	54732
HPRD ID		16738	09975
Ensembl ID		ENSG00000111481	ENSG00000184840
Uniprot IDs		P61923	Q9BVK6
PDB IDs		2HF6 5MC7	9CJK 9CJL
GO Terms Enriched among Interactors		Endoplasmic Reticulum-Golgi Intermediate Compartment Transport Vesicle Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Golgi Vesicle Transport COPI Coating Of Golgi Vesicle Endoplasmic Reticulum Membrane Intracellular Transport Vesicle-mediated Transport COPI-coated Vesicle COPI Vesicle Coat Trans-Golgi Network Transport Vesicle Intracellular Protein Transport COPI-coated Vesicle Membrane Golgi Apparatus Transport Along Microtubule Golgi Membrane Cytoskeleton-dependent Intracellular Transport Cellular Localization Establishment Of Localization In Cell Microtubule-based Transport Membrane Coat Intra-Golgi Vesicle-mediated Transport Vesicle Coating COPII-coated ER To Golgi Transport Vesicle Cytoplasmic Vesicle Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Syntaxin Binding Regulation Of Amyloid Precursor Protein Catabolic Process Protein Transport Microtubule-based Movement Secretion By Cell Positive Regulation Of Interleukin-1 Production Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Cytosol To ERGIC Protein Transport Protein Localization To ERGIC COPI-coated Vesicle Budding Organelle Transport Along Microtubule Establishment Of Protein Localization Secretion Acetylcholine Receptor Activator Activity Regulation Of Interleukin-1 Production Lipoprotein Particle Positive Regulation Of Protein Import Golgi Organization	None