EEF1D and CAMSAP2

Number of citations: 57 (PubMedID 20195357)
Data Source: BioGRID (pull down)

		EEF1D	CAMSAP2
Name		eukaryotic translation elongation factor 1 delta	calmodulin regulated spectrin associated protein family member 2
Structure			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Cytosol Eukaryotic Translation Elongation Factor 1 Complex	Cytoplasm Golgi Apparatus Centrosome Cytosol Cytoskeleton Microtubule Ciliary Basal Body Microtubule Minus-end Cell Projection Microtubule End
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding Translation Elongation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Translation Factor Activity, RNA Binding Heat Shock Protein Binding Cadherin Binding DNA-binding Transcription Factor Binding	Protein Binding Calmodulin Binding Microtubule Binding Spectrin Binding Microtubule Minus-end Binding
	Biological Process	Cytoplasmic Translational Elongation Translation Translational Elongation Cellular Response To Heat Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Ionizing Radiation	Microtubule Cytoskeleton Organization Negative Regulation Of Microtubule Depolymerization Regulation Of Microtubule Polymerization Cytoplasmic Microtubule Organization Neuron Projection Development Regulation Of Organelle Organization Regulation Of Dendrite Development Axon Development Regulation Of Golgi Organization
Pathways		Eukaryotic Translation Elongation	None
GWAS		Schizophrenia ( 31268507 )	Heel bone mineral density ( 30598549 ) Medication use (thyroid preparations) ( 31015401 ) Refractive error ( 32231278 )
Interacting Genes		45 interacting genes: ALX1 APP ARHGAP21 ASCC2 ATG7 CAMSAP2 CD48 CDK1 CDK9 CEBPA CRMP1 CSNK2A1 CTBP1 CTBP2 ECH1 EEF1G EPRS1 FILNC1 FKBP6 FOS FRA10AC1 GARS1 HEXD KARS1 KTN1 LINC01232 MAP1B NR2F1 POT1 PRKCA RELA RNF20 RNF40 RPS6KA1 SIAH1 SIAH2 SLC26A4-AS1 SNCA TERF1 TINF2 TPT1 UBE2A USP40 USP7 VARS1	4 interacting genes: ATXN1L CREBBP EEF1D UBE2I
Entrez ID		1936	23271
HPRD ID		00560	11124
Ensembl ID		ENSG00000104529	ENSG00000118200
Uniprot IDs		B2RAR6 P29692	B3KTI4 Q08AD1
PDB IDs		2MVM 2MVN 2N51 5JPO	Not available
GO Terms Enriched among Interactors		Protein Metabolic Process Shelterin Complex HULC Complex Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Amyloid Fibril Formation Negative Regulation Of Biosynthetic Process Nuclear Telomere Cap Complex Positive Regulation Of Metabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Telomere Capping TRNA Aminoacylation Positive Regulation Of Nucleobase-containing Compound Metabolic Process Identical Protein Binding Nucleic Acid Metabolic Process Diadenosine Tetraphosphate Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Macromolecule Biosynthetic Process White Fat Cell Differentiation Regulation Of Nucleobase-containing Compound Metabolic Process Symbiont-mediated Disruption Of Host Cell PML Body Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Metabolic Process Chromatin Binding Nucleobase-containing Compound Metabolic Process Regulation Of Schwann Cell Differentiation Telomere Assembly Chromatin Organization Regulation Of Protein Catabolic Process Telomeric DNA Binding Nucleus Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Response To Interleukin-1 Regulation Of Synapse Assembly Cytosol Negative Regulation Of DNA Biosynthetic Process Response To Cytokine Regulation Of Macromolecule Biosynthetic Process Response To Copper Ion Response To Peptide Regulation Of Establishment Of Protein Localization To Telomere DNA Metabolic Process DNA-binding Transcription Factor Binding Response To Xenobiotic Stimulus Nucleoplasm Regulation Of Primary Metabolic Process Ankyrin Repeat Binding	MRF Binding Regulation Of DNA-templated Transcription Histone H3K18 Acetyltransferase Activity Negative Regulation Of Transcription By RNA Polymerase II N-terminal Peptidyl-lysine Acetylation Cellular Response To Radiation DNA-binding Transcription Factor Binding Regulation Of RNA Biosynthetic Process Histone H3K27 Acetyltransferase Activity Regulation Of Transcription By RNA Polymerase II Peptide Lactyltransferase (CoA-dependent) Activity Eukaryotic Translation Elongation Factor 1 Complex Cytoplasmic Translational Elongation RING-like Zinc Finger Domain Binding SUMO Ligase Complex Small Protein Activating Enzyme Binding HLH Domain Binding SUMO Conjugating Enzyme Activity POZ Domain Binding Negative Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase I Mitotic Nuclear Membrane Reassembly Positive Regulation Of Hematopoietic Stem Cell Proliferation Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Body Nucleoplasm N-terminal Protein Amino Acid Acetylation Peptidyl-lysine Acetylation Transferase Complex Regulation Of Cellular Response To Heat Response To Radiation Acetyltransferase Activity Chromatin Binding Cellular Response To Lectin Stimulatory C-type Lectin Receptor Signaling Pathway Translation Factor Activity, RNA Binding Translation Elongation Factor Activity Transcription Factor Binding SUMO Transferase Activity Regulation Of Hematopoietic Stem Cell Proliferation Histone Acetyltransferase Complex Regulation Of Gene Expression Synaptonemal Complex Protein-lysine-acetyltransferase Activity Nuclear Membrane Reassembly Regulation Of Macromolecule Biosynthetic Process