| Name |
EBF transcription factor 1 |
paired box 5 |
| Structure |
|
|
| GO Annotations |
Cellular Component |
|
|
| Molecular Function |
|
|
| Biological Process |
|
|
| Pathways |
|
|
| Diseases |
None
|
|
| GWAS |
- Adventurousness ( 30643258
)
- Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs) ( 23648065
)
- Anorexia nervosa (excluding migration to or from binge-eating disorder or bulimia nervosa) ( 28630421
)
- Apolipoprotein A1 levels ( 32203549
)
- Birth weight ( 31043758
27680694
)
- Blood pressure ( 21909110
)
- Body size at age 10 ( 32376654
)
- Breast cancer ( 23535729
23535733
29059683
)
- Carotid intima media thickness ( 26343869
)
- Cognitive decline rate in late mild cognitive impairment ( 26252872
)
- Creatine kinase levels ( 29403010
)
- Diastolic blood pressure ( 27841878
27618452
21909115
28135244
28739976
)
- Diastolic blood pressure (cigarette smoking interaction) ( 29455858
)
- Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962
)
- Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098
)
- General risk tolerance (MTAG) ( 30643258
)
- Gestational age at birth (maternal effect) ( 28877031
)
- HDL cholesterol levels ( 32203549
)
- HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716
)
- HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716
)
- Heel bone mineral density ( 30598549
)
- Hip circumference (psychosocial stress interaction) ( 25271088
)
- Hypertension ( 30487518
21909115
)
- Hypospadias ( 25108383
)
- Inflammatory skin disease ( 25574825
)
- Liver enzyme levels (alkaline phosphatase) ( 33972514
)
- Longevity (85 years and older) ( 24688116
)
- Longevity (90 years and older) ( 24688116
)
- Lymphocyte count ( 32888494
)
- Lymphocyte percentage of white cells ( 27863252
32888494
)
- Male-pattern baldness ( 27182965
29146897
28196072
)
- Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962
)
- Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962
)
- Mean corpuscular hemoglobin concentration ( 32888494
)
- Mean platelet volume ( 32888494
)
- Mean spheric corpuscular volume ( 32888494
)
- Medication use (agents acting on the renin-angiotensin system) ( 31015401
)
- Monocyte count ( 32888494
)
- Monocyte percentage of white cells ( 32888494
27863252
)
- Neutrophil percentage of white cells ( 32888494
)
- Non-albumin protein levels ( 29403010
)
- Obesity-related traits ( 23251661
)
- Offspring birth weight ( 31043758
)
- Pericardial adipose tissue adjusted for height and weight ( 27918534
)
- Pericardial fat ( 27918534
)
- Platelet count ( 32888494
)
- Post bronchodilator FEV1 ( 26634245
)
- Preterm birth (maternal effect) ( 28877031
)
- Pulse pressure ( 27841878
28739976
30224653
28135244
30578418
)
- Pulse pressure x alcohol consumption interaction (2df test) ( 29912962
)
- Refractive error ( 32231278
)
- Reticulocyte fraction of red cells ( 32888494
)
- Serum alkaline phosphatase levels ( 33547301
)
- Smoking initiation (ever regular vs never regular) ( 30679032
)
- Smoking status (ever vs never smokers) ( 30643258
)
- Systolic blood pressure ( 21909115
30578418
27841878
27618452
28739976
26390057
28135244
)
- Systolic blood pressure (cigarette smoking interaction) ( 29455858
)
- Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962
)
- Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962
)
- Triglyceride levels ( 30698716
32203549
)
- Triglyceride levels in current drinkers ( 30698716
)
- Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716
)
- Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716
)
- Type 2 diabetes (adjusted for BMI) ( 30297969
)
- Waist circumference adjusted for body mass index ( 34021172
)
- Waist-hip ratio and HDL-C (pairwise) ( 33619380
)
|
|
| Interacting Genes |
9 interacting genes:
ATPAF2
CREBBP
ERO1A
HOMEZ
MTNR1B
PAX5
POU6F2
ZNF423
ZNF521
|
54 interacting genes:
ACOT12
AIRIM
BCAS2
CCNC
CDK3
CIB3
CKS1B
CREBBP
CSNK2A1
CXorf38
DAXX
DTX2
EBF1
ETS1
FBLN1
GNG13
GRHL2
HGS
HMBOX1
HMGB3
HOXC8
ID2
ID3
KLHL38
KPNA1
KPNA2
KRTAP10-8
KRTAP9-3
LARP4
LDLRAP1
LONRF1
MAPK1
MAPK9
MYB
NEIL2
NFYC
NGLY1
OSGIN1
PNMA5
RAD52
RB1
RNF144B
RUNX1
SAE1
SEC14L4
STAC
TBP
TLE4
TLK2
UBE2I
UBE3A
UBXN2B
UBXN7
ZMYM5
|
| Entrez ID |
1879 |
5079 |
| HPRD ID |
01256
|
01334
|
| Ensembl ID |
ENSG00000164330
|
ENSG00000196092
|
| Uniprot IDs |
B4E2U8
Q9UH73
|
C0KTE5
C0KTF5
E7EQT0
E7ERK2
E7ERW5
E7ES87
Q02548
|
| PDB IDs |
3LYR
3MQI
|
1K78
1MDM
|
| GO Terms Enriched among Interactors |
None
|
|