SEPTIN1 and SEPTIN6

Number of citations: 0 (PubMedID 16189514)
Data Source: HPRD (two hybrid)

		SEPTIN1	SEPTIN6
Name		septin 1	septin 6
Structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytoskeleton Septin Ring Synaptic Vesicle Microtubule Cytoskeleton Midbody Septin Complex Cell Division Site Meiotic Spindle	Chromosome, Centromeric Region Kinetochore Chromosome Cytoplasm Spindle Cytoskeleton Cilium Septin Ring Synaptic Vesicle Microtubule Cytoskeleton Midbody Septin Complex Motile Cilium Cell Division Site Cleavage Furrow Septin Collar Cell Projection Axon Terminus Sperm Annulus Presynapse
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Identical Protein Binding Molecular Adaptor Activity	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Molecular Adaptor Activity
	Biological Process	Spindle Assembly Involved In Female Meiosis Intracellular Protein Localization Regulation Of Exocytosis Cell Division Meiotic Metaphase Chromosome Alignment Cytoskeleton-dependent Cytokinesis	Mitotic Cytokinesis Spermatogenesis Intracellular Protein Localization Cell Differentiation Cell Division Cytoskeleton-dependent Cytokinesis
GWAS		No GWAS studies recorded	No GWAS studies recorded
Interacting Genes		24 interacting genes: AMOT APP AURKB DDIT4L DNAJB13 GORASP2 GPSM1 HSF2BP LNX1 MID2 MRPL12 NIF3L1 PICK1 PIH1D1 SDCBP SEPTIN11 SEPTIN3 SEPTIN5 SEPTIN6 SEPTIN9 TEX11 TOLLIP UBC UBE2I	15 interacting genes: CDC42EP2 CDC42EP3 CEBPA CRK KDM1A MORN4 NSD3 PLEKHF2 RHOU S100A4 SEPTIN1 SEPTIN2 SEPTIN9 SH3KBP1 TK1
Entrez ID		1731	23157
HPRD ID		15324	06716
Ensembl ID		ENSG00000180096	ENSG00000125354
Uniprot IDs		J3KNL2 Q8WYJ6	B1AMS2 Q14141 Q541S4 Q548C9
PDB IDs		6WBE	2QAG 6UPA 6WBP 7M6J
GO Terms Enriched among Interactors		Septin Ring Septin Complex Cell Division Site Cytoskeleton-dependent Cytokinesis Molecular Adaptor Activity Microtubule Cytoskeleton Cell Division Cytoplasm GTPase Activity Intracellular Protein Localization Cytoskeleton GTP Binding Regulation Of Receptor Internalization Stress Fiber Synaptonemal Complex Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Receptor Internalization Synaptic Vesicle Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Frizzled Binding Interleukin-5 Receptor Complex SUMO Conjugating Enzyme Activity Positive Regulation Of Lateral Attachment Of Mitotic Spindle Microtubules To Kinetochore Phosphoprotein Binding Septin Collar Meiotic Gene Conversion	Regulation Of Cell Shape Cell Division Site Septin Ring Septin Complex Regulation Of Cell Morphogenesis Organelle Organization Cytoskeleton-dependent Cytokinesis Microtubule Cytoskeleton Positive Regulation Of Pseudopodium Assembly Actin Cytoskeleton Cytoskeleton Organization GTPase Activity Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Regulation Of Plasma Membrane Bounded Cell Projection Organization Actin Cytoskeleton Organization Regulation Of Cell Projection Organization GTP Binding Positive Regulation Of Cell Projection Organization Non-motile Cilium Actin Filament-based Process Molecular Adaptor Activity Regulation Of Anatomical Structure Morphogenesis RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Positive Regulation Of Actin Filament Polymerization Cytoskeletal Regulatory Protein Binding Histone H3K4 Dimethyltransferase Activity Histone H3K27 Dimethyltransferase Activity Cytoskeleton Regulation Of Cell Projection Assembly Response To Vitamin B2 C/EBP Complex Helper T Cell Diapedesis Protein Phosphorylated Amino Acid Binding Response To Cholecystokinin Meiotic Metaphase Chromosome Alignment Thymidine Kinase Activity Endomembrane System Rho Protein Signal Transduction Regulation Of Cellular Component Size Actin Filament Organization Small GTPase-mediated Signal Transduction Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity CHOP-C/EBP Complex Regulation Of Stem Cell Proliferation Identical Protein Binding Regulation Of Developmental Process Cerebral Cortex Development Cerebellar Neuron Development Epithelial To Mesenchymal Transition