ZMAT2 and AMH

Number of citations: 38 (PubMedID 21988832)
Data Source: BioGRID (two hybrid)

		ZMAT2	AMH
Name		zinc finger matrin-type 2	anti-Mullerian hormone
Structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome	Extracellular Region Extracellular Space
	Molecular Function	Nucleic Acid Binding DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Signaling Receptor Binding Type II Transforming Growth Factor Beta Receptor Binding Transforming Growth Factor Beta Receptor Binding Hormone Activity Protein Binding Growth Factor Activity
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing	Ovarian Follicle Development Preantral Ovarian Follicle Growth Urogenital System Development Mullerian Duct Regression Cell-cell Signaling Gonadal Mesoderm Development Sex Determination Sex Differentiation Gonad Development Response To Xenobiotic Stimulus Positive Regulation Of Gene Expression Cell Differentiation Leydig Cell Differentiation Development Of Primary Male Sexual Characteristics Positive Regulation Of SMAD Protein Signal Transduction Anti-Mullerian Hormone Receptor Signaling Pathway Negative Regulation Of Ovarian Follicle Development
Pathways		mRNA Splicing - Major Pathway	Signaling by BMP Transcriptional regulation of testis differentiation
Diseases		None	46,XY disorders of sex development (Other), including: Persistent Mullerian duct syndrome; Hypospadias; Cryptorchidism
GWAS		Major depressive disorder ( 27479909 ) Refractive error ( 32231278 ) Schizophrenia ( 28991256 29483656 ) Serum immune biomarker levels ( 32066700 ) Systolic blood pressure ( 30224653 )	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098 ) Pulse pressure ( 26390057 27618447 30487518 )
Interacting Genes		41 interacting genes: AK8 AMH BICD2 CALCOCO1 CBY2 CCDC57 CDR2 CEBPA CEP76 ERBB2 FSD2 FXR1 FXR2 GOLGA2 GOLGA6L9 GRIPAP1 HAP1 HMBOX1 IKZF1 KANK2 KRT40 LZTS2 MEOX2 MTUS2 NAB2 NUTF2 PHC2 PICK1 PRPH SPAG5 SSX2IP TFEC TFIP11 TNIP1 TRAF2 TRIM36 TRIM37 TSEN15 VPS52 ZBTB14 ZBTB8A	6 interacting genes: AMHR2 ARL8B EGFR ETV5 PCSK5 ZMAT2
Entrez ID		153527	268
HPRD ID		08094	02979
Ensembl ID		ENSG00000146007	ENSG00000104899
Uniprot IDs		Q96NC0	P03971
PDB IDs		5O9Z 6AHD 7AAV 7ABF 7ABG 7ABI 8H6K 8Q7N 8QO9 8QPE 8QZS	7L0J
GO Terms Enriched among Interactors		Regulation Of Microtubule-based Process Cytoskeleton Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Centrosome Negative Regulation Of Nucleobase-containing Compound Metabolic Process Identical Protein Binding Protein Binding Negative Regulation Of RNA Metabolic Process Positive Regulation Of Long-term Neuronal Synaptic Plasticity MRNA Transport Cytoplasm Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Microtubule-based Process RNA Transport Cellular Localization Microtubule Cytoskeleton Organization Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Translation Regulator Activity Cytosol	Mullerian Duct Regression Anti-Mullerian Hormone Receptor Signaling Pathway Anti-Mullerian Hormone Receptor Activity Transforming Growth Factor Beta Receptor Activity, Type II Regulation Of Protein Kinase C Signaling Epidermal Growth Factor Binding Embryonic Organ Development Positive Regulation Of Protein Kinase C Signaling Epidermal Growth Factor Receptor Activity Biological Process Involved In Interaction With Host Shc-EGFR Complex Multivesicular Body, Internal Vesicle Lumen Germ-line Stem Cell Division Regulation Of Branching Involved In Mammary Gland Duct Morphogenesis Male Germ-line Stem Cell Asymmetric Division Viral Life Cycle Cytokine Precursor Processing Renin Secretion Into Blood Stream Viral Process Calcium Ion Regulated Lysosome Exocytosis Cytolytic Granule Membrane Antigen Processing And Presentation Following Phagocytosis Antigen Processing And Presentation Of Polysaccharide Antigen Via MHC Class II Endosome To Lysosome Transport Of Low-density Lipoprotein Particle Protein Localization To Early Endosome Viral Exocytosis Skeletal System Development