ARL6IP6 and ARL6

Number of citations: 0 (PubMedID 10508919)
Data Source: HPRD (two hybrid)

		ARL6IP6	ARL6
Name		ARF like GTPase 6 interacting protein 6	ARF like GTPase 6
Structure		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Inner Membrane Membrane	Nucleoplasm Cytoplasm Cytosol Cytoskeleton Axonemal Microtubule Plasma Membrane Cilium Axoneme Microtubule Cytoskeleton Membrane Membrane Coat Cell Projection Extracellular Exosome
	Molecular Function	Protein Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Phospholipid Binding Metal Ion Binding
	Biological Process	None	Protein Targeting To Membrane Intracellular Protein Transport Determination Of Left/right Symmetry Brain Development Visual Perception Regulation Of Smoothened Signaling Pathway Retina Layer Formation Protein Transport Wnt Signaling Pathway Vesicle-mediated Transport Cell Projection Organization Melanosome Transport Fat Cell Differentiation Protein Polymerization Cilium Assembly Protein Localization To Cilium Protein Localization To Non-motile Cilium Protein Transport From Ciliary Membrane To Plasma Membrane
Pathways		None	BBSome-mediated cargo-targeting to cilium
Diseases		None	Bardet-Biedl syndrome (BBS) Retinitis pigmentosa (RP)
GWAS		Lung cancer ( 28604730 ) Pancreatic cancer ( 29422604 ) Recurrent major depressive disorder x sex interaction ( 34099189 ) Refractive error ( 32231278 )	Male infertility ( 19478329 )
Interacting Genes		17 interacting genes: APP AQP6 ARL6 CLRN2 CMTM2 DRD2 EBP GJA8 GPR61 MGST3 RUSF1 SLC10A1 TBXA2R TIMMDC1 TMEM205 TMEM80 TMEM86B	6 interacting genes: ARL6IP1 ARL6IP4 ARL6IP5 ARL6IP6 ATL2 SEC61B
Entrez ID		151188	84100
HPRD ID		12485	10588
Ensembl ID		ENSG00000177917	ENSG00000113966
Uniprot IDs		A0A8I5KQ30 B3KMZ5 Q8N6S5	Q9H0F7
PDB IDs		Not available	2H57
GO Terms Enriched among Interactors		Membrane	Regulation Of L-glutamate Import Across Plasma Membrane Sec61 Translocon Complex Endoplasmic Reticulum Tubular Network Membrane Organization Endoplasmic Reticulum Membrane Organization Endoplasmic Reticulum Tubular Network Organization Cellular Localization Endoplasmic Reticulum Membrane Endoplasmic Reticulum Sec Complex Endoplasmic Reticulum Organization Negative Regulation Of L-glutamate Import Across Plasma Membrane Regulation Of Amine Transport