TMEM37 and PLA2G12A

Number of citations: 38 (PubMedID 21988832)
Data Source: BioGRID (two hybrid)

		TMEM37	PLA2G12A
Name		transmembrane protein 37	phospholipase A2 group XIIA
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane Monoatomic Ion Channel Complex	Extracellular Region Cytoplasm
	Molecular Function	Voltage-gated Monoatomic Ion Channel Activity Calcium Channel Activity	Phospholipase A2 Activity Calcium Ion Binding Protein Binding Hydrolase Activity Metal Ion Binding Calcium-dependent Phospholipase A2 Activity
	Biological Process	Monoatomic Ion Transport Calcium Ion Transport Monoatomic Ion Transmembrane Transport Calcium Ion Transmembrane Transport	Lipid Metabolic Process Phospholipid Metabolic Process Lipid Catabolic Process Arachidonate Secretion
Pathways		None	Acyl chain remodelling of PC Acyl chain remodelling of PS Acyl chain remodelling of PE Acyl chain remodelling of PI Acyl chain remodelling of PG Synthesis of PA
GWAS		No GWAS studies recorded	HDL cholesterol ( 30275531 ) Lipoprotein (a) levels ( 33730874 ) Mean spheric corpuscular volume ( 32888494 ) Triglycerides ( 30275531 )
Interacting Genes		6 interacting genes: HBP1 MPP3 ORM1 PLA2G12A SPIB UBQLN1	8 interacting genes: DVL2 MEF2C RB1 RPS15 RPS6 TMEM37 UMPS YWHAG
Entrez ID		140738	81579
HPRD ID		15536	17858
Ensembl ID		ENSG00000171227	ENSG00000123739
Uniprot IDs		E7EMC0 Q86SV2 Q8WXS4	Q542Y6 Q9BZM1
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		None	Ribosomal Small Subunit Assembly Cytoplasmic Translation Cell Morphogenesis Involved In Neuron Differentiation Response To Insulin Small Ribosomal Subunit Positive Regulation Of Signal Transduction By P53 Class Mediator Response To Hormone Cytosolic Small Ribosomal Subunit Outflow Tract Morphogenesis Heart Looping Embryonic Heart Tube Morphogenesis Chondrocyte Differentiation Striated Muscle Cell Differentiation Cellular Response To Oxygen-containing Compound Cellular Response To Hormone Stimulus Cellular Response To Xenobiotic Stimulus Sinoatrial Valve Morphogenesis Heart Valve Morphogenesis Negative Regulation Of Protein Kinase Activity Response To Peptide Hormone Ribosomal Small Subunit Biogenesis Translation Orotidine-5'-phosphate Decarboxylase Activity Orotate Phosphoribosyltransferase Activity Intracellular Signal Transduction Negative Regulation Of Kinase Activity TOR Signaling Muscle Cell Fate Determination Nephron Tubule Epithelial Cell Differentiation Cellular Response To Trichostatin A Cellular Response To Insulin Stimulus Cytosolic Ribosome Positive Regulation Of Intracellular Signal Transduction Muscle Cell Differentiation Negative Regulation Of Protein Phosphorylation Epithelial Tube Morphogenesis Convergent Extension Involved In Neural Plate Elongation Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Macrophage Apoptotic Process Primary Heart Field Specification Glomerulus Morphogenesis Negative Regulation Of Phosphorylation Chromatin Lock Complex 'de Novo' UMP Biosynthetic Process Protein Kinase C Inhibitor Activity Osteoblast Differentiation Cytosol Regulation Of Synaptic Activity Sister Chromatid Biorientation Maintenance Of Mitotic Sister Chromatid Cohesion