TMEM37 and HBP1

Number of citations: 38 (PubMedID 21988832)
Data Source: BioGRID (two hybrid)

		TMEM37	HBP1
Name		transmembrane protein 37	HMG-box transcription factor 1
Structure		No pdb structure
GO Annotations	Cellular Component	Membrane Monoatomic Ion Channel Complex	Chromatin Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	Voltage-gated Monoatomic Ion Channel Activity Calcium Channel Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding RNA Binding Protein Binding
	Biological Process	Monoatomic Ion Transport Calcium Ion Transport Monoatomic Ion Transmembrane Transport Calcium Ion Transmembrane Transport	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Wnt Signaling Pathway Regulation Of Cell Cycle
GWAS		No GWAS studies recorded	Metabolite levels ( 23823483 )
Interacting Genes		6 interacting genes: HBP1 MPP3 ORM1 PLA2G12A SPIB UBQLN1	20 interacting genes: ANKRD2 CASP8 CD2AP CREBBP EP300 ESR1 EWSR1 HDAC1 KIFBP RB1 RB1CC1 RBL2 SAP30 SIN3A SMAD1 TCF4 TMEM37 UBE2H WDR26 ZNF212
Entrez ID		140738	26959
HPRD ID		15536	13634
Ensembl ID		ENSG00000171227	ENSG00000105856
Uniprot IDs		E7EMC0 Q86SV2 Q8WXS4	B4DJ36 O60381
PDB IDs		Not available	2E6O 3QVE
GO Terms Enriched among Interactors		None	Transcription Regulator Complex RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Histone H3K27 Acetyltransferase Activity Chromatin Cell Differentiation Sin3-type Complex Histone H3K18 Acetyltransferase Activity Transcription Corepressor Activity N-terminal Peptidyl-lysine Acetylation Regulation Of Transcription By RNA Polymerase II Peptide Lactyltransferase (CoA-dependent) Activity Negative Regulation Of Stem Cell Population Maintenance Developmental Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II TFIIB-class Transcription Factor Binding Regulation Of Lipid Kinase Activity Rhythmic Process Regulation Of Gene Expression Transcription Coregulator Activity Regulation Of Macromolecule Biosynthetic Process Nucleus Cellular Developmental Process Protein-containing Complex Regulation Of RNA Metabolic Process Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Histone Deacetylase Complex Positive Regulation Of Stem Cell Population Maintenance Transcription Coactivator Binding Chromatin Organization Regulation Of Protein Localization To Nucleus Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Cell Differentiation Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Programmed Cell Death Regulation Of Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II DNA Binding DNA-binding Transcription Factor Binding Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Developmental Process P53 Binding Chromatin Remodeling Negative Regulation Of Biosynthetic Process N-terminal Protein Amino Acid Acetylation Regulation Of Stem Cell Population Maintenance