FLACC1 and TXNDC5

Number of citations: 56 (PubMedID 25416956)
Data Source: BioGRID (two hybrid)

		FLACC1	TXNDC5
Name		flagellum associated containing coiled-coil domains 1	thioredoxin domain containing 5
Structure		No pdb structure
GO Annotations	Cellular Component	Outer Dense Fiber Cytoplasm Cilium Cytoplasmic Vesicle Motile Cilium Sperm Flagellum Cell Projection	Extracellular Region Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endomembrane System Azurophil Granule Lumen Lysosomal Lumen Intracellular Organelle Lumen Extracellular Exosome
	Molecular Function	Protein Binding	Protein Disulfide Isomerase Activity Protein Binding Protein-disulfide Reductase Activity Oxidoreductase Activity Isomerase Activity
	Biological Process	None	Protein Folding Negative Regulation Of Apoptotic Process
Pathways		None	Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Neutrophil degranulation
GWAS		No GWAS studies recorded	Blood protein levels ( 30072576 ) High chromosomal aberration frequency (chromatid type) ( 31586183 ) Mean corpuscular hemoglobin ( 32888494 ) Pelvic organ prolapse ( 32184442 )
Interacting Genes		22 interacting genes: ATP6V1H BLK CRK DISC1 DVL3 FAM90A1 INO80B LGALS14 LONRF1 PRPF31 SPG21 SSX2 SSX2B SSX4 SSX4B STK16 SULT2B1 TCL1A TEPSIN TRIM41 TXNDC5 YES1	29 interacting genes: APP AR BLZF1 CEBPA EDEM3 EFEMP1 FLACC1 GMPPB KRT38 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-12 KRTAP4-2 LHX4 MGAT5B NOTCH2NLA OGT PJA1 PRDX2 RAB3IP SPRY2 TRIM23 TRIM42 TRIP6 UBQLN2
Entrez ID		130540	81567
HPRD ID		12444	18249
Ensembl ID		ENSG00000155749	ENSG00000239264
Uniprot IDs		A8K8B8 Q96Q35	A0A024QZV0 Q8NBS9
PDB IDs		Not available	2DIZ 3UJ1 3UVT 3WGD 3WGE 3WGX 8EKY
GO Terms Enriched among Interactors		Non-membrane Spanning Protein Tyrosine Kinase Activity Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta	Keratin Filament Intermediate Filament Protein Glycosylation Macromolecule Glycosylation Glycosylation Hair Cycle