COL4A1 and SERPINE2

  • Number of citations: 0 (PubMedID 8006028)
  • Data Source: HPRD (in vivo)

COL4A1

SERPINE2

Name collagen type IV alpha 1 chain serpin family E member 2
Structure PDB 1LI1 PDB 4DY0
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Diseases None
GWAS
  • Age-related nuclear cataracts ( 24951543 )
  • Arterial stiffness ( 20031579 )
  • Behavioral disturbance or psychiatric symptoms and prion disease ( 25897833 )
  • Coronary artery disease ( 32469254 33020668 24262325 26343387 29212778 )
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975 )
  • Coronary heart disease ( 21378990 )
  • Diastolic blood pressure response to thiazide and thiazide-like diuretics in hypertension ( 31754133 )
  • Estimated glomerular filtration rate after 1 year in renal transplantation (donor effect) ( 30920136 )
  • Hip circumference adjusted for BMI ( 34021172 )
  • Hip index ( 34021172 )
  • Intraocular pressure ( 31959993 29785010 )
  • Lateral ventricle volume ( 31530798 )
  • Liver enzyme levels (gamma-glutamyl transferase) ( 33972514 )
  • Lymphocyte count ( 32888494 )
  • Mean platelet volume ( 32888494 )
  • Metabolite levels ( 23823483 )
  • Monocyte count ( 32888494 27863252 )
  • Myocardial infarction ( 33532862 26343387 )
  • Night sleep phenotypes ( 27126917 )
  • Non-lobar intracerebral hemorrhage (MTAG) ( 31430377 )
  • Obesity-related traits ( 23251661 )
  • Peripheral artery disease ( 31285632 )
  • Platelet count ( 32888494 )
  • Platelet distribution width ( 32888494 )
  • Plateletcrit ( 32888494 )
  • Pulse pressure ( 30578418 )
  • Stroke ( 30383316 )
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993 )
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993 )
  • Waist-hip index ( 34021172 )
  • Waist-to-hip ratio adjusted for BMI ( 28552196 34021172 )
  • Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil) ( 23648065 )
  • Blood protein levels ( 30072576 )
  • Cerebrospinal T-tau levels ( 28247064 )
  • Cytokine levels ( 31679650 )
  • Cytokine network levels (multivariate analysis) ( 31679650 )
  • Height ( 20881960 31562340 )
  • Inflammatory biomarkers (multivariate analysis) ( 33110245 )
  • Mean platelet volume ( 27863252 32888494 )
  • Platelet-derived growth factor BB levels ( 27989323 )
Novel Interactors 1 novel interactors: CXCR4 None recorded
Interacting Genes 30 interacting genes: ACHE APCS APP BGN BMP3 CD93 COL18A1 COL4A2 COL7A1 DCN DISC1 FBLN2 FN1 HABP2 MAG MATN2 MMP9 NID1 NID2 OSM PDGFA PDGFB SAA1 SAA2 SAA4 SERPINE2 SMAD1 TGFBI TGM2 THBS1 9 interacting genes: COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 ETS2 F2 FAM9B
Entrez ID 1282 5270
HPRD ID 00359 01510
Ensembl ID ENSG00000187498 ENSG00000135919
Uniprot IDs A5PKV2 P02462 P07093
PDB IDs 1LI1 5NAX 5NAY 6MPX 4DY0 4DY7
GO Terms Enriched among Interactors