DNTTIP1 and DNTT

Number of citations: 0 (PubMedID 11473582)
Data Source: HPRD (in vitro, in vivo, two hybrid)

		DNTTIP1	DNTT
Name		deoxynucleotidyltransferase terminal interacting protein 1	DNA nucleotidylexotransferase
Structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Nucleus Nucleoplasm Chromosome Nucleolus	Chromatin Euchromatin Nucleus Nucleoplasm Cytosol Nuclear Matrix
	Molecular Function	DNA Binding Protein Binding Nucleosome Binding Protein Homodimerization Activity	DNA Binding DNA-directed DNA Polymerase Activity DNA Nucleotidylexotransferase Activity Protein Binding Transferase Activity Nucleotidyltransferase Activity DNA Polymerase Activity Metal Ion Binding
	Biological Process	None	DNA Metabolic Process DNA Repair Double-strand Break Repair Via Nonhomologous End Joining DNA Modification Response To ATP DNA Biosynthetic Process
Pathways		Negative Regulation of CDH1 Gene Transcription	None
Drugs		None	2',3'-Dideoxyadenosine triphosphate
GWAS		Mean platelet volume ( 27863252 32888494 ) Temporal pole volume ( 31530798 )	No GWAS studies recorded
Interacting Genes		12 interacting genes: ANP32B DNTT E2F6 EAF1 HMBOX1 HOMEZ KDM1A MAGEA6 MFAP1 PICK1 TRIM55 TRIM63	9 interacting genes: ABTB2 DNTTIP1 DNTTIP2 MEI4 PCNA PRPF19 REL TCF4 XRCC6
Entrez ID		116092	1791
HPRD ID		16831	08925
Ensembl ID		ENSG00000101457	ENSG00000107447
Uniprot IDs		Q9H147	P04053
PDB IDs		2MWI 4D6K 6Z2J 6Z2K	2COE 5W4E
GO Terms Enriched among Interactors		Nucleus Telomeric DNA Binding	Damaged DNA Binding DNA End Binding DNA Metabolic Process Telomere Maintenance Chromosome Organization Double-strand Break Repair Via Nonhomologous End Joining Ku70:Ku80 Complex Chromosome PCNA Complex PCNA-p21 Complex Replisome DNA Polymerase Processivity Factor Activity Mitotic Telomere Maintenance Via Semi-conservative Replication Dinucleotide Insertion Or Deletion Binding Purine-specific Mismatch Base Pair DNA N-glycosylase Activity Beta-catenin-TCF7L2 Complex Negative Regulation Of Skeletal Muscle Tissue Growth