POLR1G and POLR1E

Number of citations: 57 (PubMedID 15226435)
Data Source: HPRD (in vitro)

		POLR1G	POLR1E
Name		RNA polymerase I subunit G	RNA polymerase I subunit E
Structure
GO Annotations	Cellular Component	RNA Polymerase I Transcription Regulator Complex DNA-directed RNA Polymerase Complex Fibrillar Center Nucleus Nucleoplasm Chromosome Nucleolus RNA Polymerase I Complex Mitochondrion Cytosol	DNA-directed RNA Polymerase Complex Fibrillar Center Nucleus Nucleoplasm Nucleolus RNA Polymerase I Complex
	Molecular Function	RNA Binding Protein Binding	RNA Polymerase I General Transcription Initiation Factor Binding DNA Binding Protein Binding
	Biological Process	Transcription By RNA Polymerase I Transcription Initiation At RNA Polymerase I Promoter Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway RRNA Transcription	RNA Polymerase I Preinitiation Complex Assembly DNA-templated Transcription Transcription Initiation At RNA Polymerase I Promoter Transcription Elongation By RNA Polymerase I Nucleolar Large RRNA Transcription By RNA Polymerase I
Pathways		NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination	NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
GWAS		No GWAS studies recorded	No GWAS studies recorded
Interacting Genes		6 interacting genes: CD3E NFKBIB POLR1C POLR1E TAF1A UBTF	9 interacting genes: NFKBIB OGT POLR1A POLR1B POLR1C POLR1G SIRT7 TAF1C UBTF
Entrez ID		10849	64425
HPRD ID		00125	15096
Ensembl ID		ENSG00000117877	ENSG00000137054
Uniprot IDs		O15446	B4E005 Q9GZS1
PDB IDs		7OB9 7OBA 7OBB 7VBA 7VBB 7VBC 8A43	7OB9 7OBA 7OBB 7VBA 7VBB 7VBC 8A43
GO Terms Enriched among Interactors		Transcription By RNA Polymerase I DNA-templated Transcription Transcription Initiation At RNA Polymerase I Promoter Nucleobase-containing Compound Biosynthetic Process RNA Polymerase I Preinitiation Complex Assembly RNA Polymerase I Complex Fibrillar Center RNA Metabolic Process Macromolecule Biosynthetic Process DNA-directed RNA Polymerase Complex Nucleolus Transcription Preinitiation Complex Assembly Nucleic Acid Metabolic Process DNA-templated Transcription Initiation RNA Polymerase I General Transcription Initiation Factor Binding Positive Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Maintenance Of Protein Location In Plasma Membrane RNA Polymerase I Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Cell Communication By Electrical Coupling Gamma-delta T Cell Receptor Complex Nucleobase-containing Compound Metabolic Process RNA Polymerase I Transcription Regulator Complex T Cell Anergy Regulation Of Glucose Mediated Signaling Pathway Nucleolar Large RRNA Transcription By RNA Polymerase I Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential RNA Polymerase I General Transcription Initiation Factor Activity RNA Polymerase Transcription Factor SL1 Complex Cellular Response To Magnesium Ion Positive Regulation Of T Cell Anergy Positive Regulation Of Cell-cell Adhesion Mediated By Integrin T Cell Tolerance Induction Protein-DNA Complex Assembly Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Spectrin-associated Cytoskeleton Channel Activator Activity Regulation Of Membrane Depolarization During Action Potential Negative Regulation Of Voltage-gated Potassium Channel Activity Negative Regulation Of Delayed Rectifier Potassium Channel Activity Alpha-beta T Cell Receptor Complex Signal Complex Assembly Regulation Of T Cell Anergy Transcription Elongation By RNA Polymerase I Regulation Of Delayed Rectifier Potassium Channel Activity CD4-positive, Alpha-beta T Cell Proliferation RNA Polymerase I Core Promoter Sequence-specific DNA Binding Positive Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Positive Regulation Of T Cell Tolerance Induction Positive Regulation Of Membrane Potential Protein Localization To Axon	Transcription By RNA Polymerase I DNA-templated Transcription RNA Polymerase I Complex RRNA Transcription Nucleobase-containing Compound Biosynthetic Process Macromolecule Biosynthetic Process DNA-directed RNA Polymerase Complex Transcription Initiation At RNA Polymerase I Promoter Fibrillar Center RNA Metabolic Process Nucleolus DNA-directed RNA Polymerase Activity Nucleic Acid Metabolic Process RNA Polymerase I General Transcription Initiation Factor Activity DNA/RNA Hybrid Binding 5'-3' RNA Polymerase Activity Nucleobase-containing Compound Metabolic Process RRNA Metabolic Process DNA-templated Transcription Initiation RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I Preinitiation Complex Assembly Macromolecule Metabolic Process Positive Regulation Of Transcription By RNA Polymerase I Nucleoplasm Regulation Of Transcription By RNA Polymerase I Regulation Of Gluconeogenesis Chromosome Transcription Preinitiation Complex Assembly Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Nucleolus Organizer Region Negative Regulation Of Protein Ubiquitination Nucleus RNA Polymerase I Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of Protein Localization To Nucleolus Histone H3K18 Deacetylase Activity, NAD-dependent NAD-dependent Protein-lysine Depropionylase Activity Protein Deglutarylation Protein-succinyllysine Desuccinylase Activity Protein Depropionylation Protein-glutaryllysine Deglutarylase Activity Nucleologenesis Negative Regulation Of Post-translational Protein Modification Nucleotidyltransferase Activity Regulation Of Glucose Metabolic Process Protein O-acetylglucosaminyltransferase Activity RNA Polymerase I Transcription Regulator Complex Ribonucleoside Binding Chromatin Binding Regulation Of Glucose Mediated Signaling Pathway