CGB3 and FSHB

Number of citations: 0 (PubMedID 10563789)
Data Source: HPRD (in vitro)

		CGB3	FSHB
Name		chorionic gonadotropin subunit beta 3	follicle stimulating hormone subunit beta
Structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Pituitary Gonadotropin Complex	Extracellular Region Extracellular Space Cytoplasm Follicle-stimulating Hormone Complex
	Molecular Function	Signaling Receptor Binding Hormone Activity Protein Binding	Signaling Receptor Binding Hormone Activity Protein Binding Follicle-stimulating Hormone Activity
	Biological Process	Apoptotic Process Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Female Gamete Generation Hormone-mediated Signaling Pathway	Ovarian Follicle Development Progesterone Biosynthetic Process Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Spermatogenesis Female Gamete Generation Female Pregnancy Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Positive Regulation Of Steroid Biosynthetic Process Positive Regulation Of Cell Migration Follicle-stimulating Hormone Signaling Pathway Regulation Of Osteoclast Differentiation Positive Regulation Of Bone Resorption Positive Regulation Of Transcription By RNA Polymerase II Sertoli Cell Proliferation
Pathways		Glycoprotein hormones TFAP2 (AP-2) family regulates transcription of growth factors and their receptors	Glycoprotein hormones Hormone ligand-binding receptors G alpha (s) signalling events
GWAS		No GWAS studies recorded	Body mass index ( 25673413 ) Endometriosis ( 28537267 ) Endometriosis or migraine ( 32121467 ) Length of menstrual cycle ( 30202859 26732621 ) Luteinizing hormone levels in polycystic ovary syndrome ( 26284813 ) Menarche (age at onset) ( 25231870 27182965 ) Menopause (age at onset) ( 26414677 ) Metabolite levels ( 23823483 ) Number of twin births ( 30760885 ) Polycystic ovary syndrome ( 26416764 26284813 30566500 ) Polycystic ovary syndrome (adjusted for age) ( 34791234 ) Polycystic ovary syndrome (indeterminate subtype) ( 32574161 ) Polycystic ovary syndrome (reproductive subtype) ( 32574161 ) Refractive error ( 32231278 ) Sex hormone levels ( 26014426 ) Spherical equivalent or myopia (age of diagnosis) ( 29808027 ) Spontaneous dizygotic twinning ( 27132594 ) Urate levels ( 31578528 ) Uterine fibroids ( 31649266 )
Interacting Genes		7 interacting genes: APP CFTR CGA FSHB LHCGR NLGN3 SMCP	3 interacting genes: CGA CGB3 FSHR
Entrez ID		1082	2488
HPRD ID		00343	00644
Ensembl ID		ENSG00000104827	ENSG00000131808
Uniprot IDs		A0A0F7RQP8 P0DN86	A0A0F7RQE8 P01225
PDB IDs		1HCN 1HRP 1QFW 7FIG 7FIH 7FII	1FL7 1XWD 4AY9 4MQW 8I2G
GO Terms Enriched among Interactors		Follicle-stimulating Hormone Activity Follicle-stimulating Hormone Complex Ovulation Cycle Process Follicle-stimulating Hormone Signaling Pathway Reproductive Process Regulation Of Steroid Biosynthetic Process Regulation Of Steroid Metabolic Process Regulation Of Hormone Levels Regulation Of Lipid Biosynthetic Process Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of Biological Quality Positive Regulation Of Steroid Biosynthetic Process Rhythmic Process Positive Regulation Of Steroid Metabolic Process G Protein-coupled Receptor Signaling Pathway Ovarian Follicle Development Modulation Of Excitatory Postsynaptic Potential Cognition Cellular Response To CAMP Developmental Process Involved In Reproduction Regulation Of Lipid Metabolic Process Amyloid-beta Complex Developmental Growth Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Choriogonadotropin Hormone Binding Choriogonadotropin Hormone Receptor Activity Luteinizing Hormone Receptor Activity Steroid Biosynthetic Process Regulation Of Membrane Potential Response To CAMP Acetylcholine Receptor Activator Activity Protein-folding Chaperone Binding PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Developmental Process Golgi Lumen Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway	Pituitary Gonadotropin Complex Follicle-stimulating Hormone Signaling Pathway Hormone-mediated Signaling Pathway Ovulation Cycle Process Female Gamete Generation G Protein-coupled Receptor Signaling Pathway Hormone Activity Gonad Development Follicle-stimulating Hormone Receptor Activity Regulation Of Acetylcholine Metabolic Process Follicle-stimulating Hormone Secretion Follicle-stimulating Hormone Activity Follicle-stimulating Hormone Complex Primary Ovarian Follicle Growth Reproductive Structure Development Reproductive Process Rhythmic Process Luteinizing Hormone Secretion Gonadotropin Secretion Sertoli Cell Proliferation Cellular Response To Hormone Stimulus Intracellular Water Homeostasis Regulation Of Protein Kinase A Signaling Developmental Growth Protein-hormone Receptor Activity Cellular Response To Follicle-stimulating Hormone Stimulus Thyroid Hormone Generation Regulation Of Hormone Levels Gamete Generation Response To Follicle-stimulating Hormone Negative Regulation Of Bone Resorption Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Sertoli Cell Development Negative Regulation Of Bone Remodeling Transcytosis Sperm DNA Condensation Cellular Response To Gonadotropin Stimulus Thyroid Hormone Metabolic Process Response To Hormone Uterus Development Female Gonad Development Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Response To Gonadotropin Thyroid Gland Development Regulation Of Signaling Receptor Activity Positive Regulation Of Steroid Biosynthetic Process Negative Regulation Of Organ Growth Cell Volume Homeostasis Peptide Hormone Binding Regulation Of Hormone Metabolic Process