AKAP3 and ROPN1B

Number of citations: 0 (PubMedID 11278869)
Data Source: HPRD (two hybrid, in vitro)

		AKAP3	ROPN1B
Name		A-kinase anchoring protein 3	rhophilin associated tail protein 1B
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Nucleus Cytoplasm Cilium Cytoplasmic Vesicle Motile Cilium Sperm Fibrous Sheath Cell Projection Sperm Midpiece Sperm Principal Piece	Cytoplasm Cilium Motile Cilium Cell Projection
	Molecular Function	Protein Binding Protein Kinase A Binding	Protein Binding Signaling Receptor Complex Adaptor Activity Protein Heterodimerization Activity
	Biological Process	Blastocyst Hatching Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Single Fertilization Acrosome Reaction Intracellular Protein Localization Flagellated Sperm Motility Establishment Of Protein Localization	Rho Protein Signal Transduction Spermatogenesis Acrosome Reaction Fusion Of Sperm To Egg Plasma Membrane Involved In Single Fertilization Flagellated Sperm Motility Cilium Organization Sperm Capacitation Protein Localization To Cilium Cytoskeleton-dependent Cytokinesis Cell-cell Adhesion
GWAS		Gut microbiota (bacterial taxa) ( 27723756 )	No GWAS studies recorded
Interacting Genes		8 interacting genes: AKAP4 BRAP GNA13 PRKAR2A ROPN1 ROPN1B ROPN1L SPA17	2 interacting genes: AKAP3 SNCA
Entrez ID		10566	152015
HPRD ID		05256	17985
Ensembl ID		ENSG00000111254	ENSG00000114547
Uniprot IDs		O75969 V9HWD4	A0A140VKG6 Q9BZX4
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Cilium Movement Motile Cilium Sperm Capacitation Sperm Motility Flagellated Sperm Motility Cilium-dependent Cell Motility Cilium Movement Involved In Cell Motility Microtubule-based Movement Cilium Sperm Fibrous Sheath CAMP-dependent Protein Kinase Complex Microtubule-based Process Developmental Process Involved In Reproduction Cell Maturation Sperm Principal Piece Developmental Maturation Reproductive Process Small GTPase-mediated Signal Transduction Epithelial Cilium Movement Involved In Extracellular Fluid Movement Extracellular Transport Cilium Organization Protein Localization To Cilium Rho Protein Signal Transduction Cytoplasm Cell Motility D5 Dopamine Receptor Binding Single Fertilization Male Gamete Generation Spermatogenesis Sperm End Piece Gamete Generation Cell Projection Fertilization Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Rho-activating G Protein-coupled Receptor Signaling Pathway CAMP-dependent Protein Kinase Regulator Activity Microtubule-based Transport CAMP-dependent Protein Kinase Inhibitor Activity Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Nucleotide-activated Protein Kinase Complex Intracellular Signal Transduction Intracellular Signaling Cassette Radial Spoke Plasma Membrane Bounded Cell Projection Organization Protein Kinase A Catalytic Subunit Binding Sperm Head-tail Coupling Apparatus Guanyl Nucleotide Binding Acrosome Reaction Fusion Of Sperm To Egg Plasma Membrane Involved In Single Fertilization Sperm Flagellum Assembly	Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Negative Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Dopamine Metabolic Process Regulation Of Serotonin Uptake Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Catecholamine Metabolic Process Dopamine Uptake Involved In Synaptic Transmission Mitochondrial ATP Synthesis Coupled Electron Transport Cuprous Ion Binding Regulation Of Chaperone-mediated Autophagy Response To Iron(II) Ion Dopamine Biosynthetic Process Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Cellular Respiration Negative Regulation Of Oxidative Phosphorylation Sperm Fibrous Sheath Regulation Of Acyl-CoA Biosynthetic Process Supramolecular Fiber Catecholamine Uptake Dopamine Uptake Positive Regulation Of Inositol Phosphate Biosynthetic Process SNARE Complex Assembly Cellular Response To Epinephrine Stimulus Positive Regulation Of Receptor Recycling Regulation Of SNARE Complex Assembly Negative Regulation Of Microtubule Polymerization Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway ATP Synthesis Coupled Electron Transport Synaptic Transmission, Dopaminergic Response To Epinephrine Positive Regulation Of Neurotransmitter Secretion Regulation Of Hydrogen Peroxide Metabolic Process Platelet Alpha Granule Membrane Dynein Complex Binding Synaptic Vesicle Priming Dopamine Transport Inclusion Body Neurotransmitter Reuptake Catecholamine Biosynthetic Process Response To Magnesium Ion Behavioral Response To Cocaine