OLFM4 and SYNE4

  • Number of citations: 56 (PubMedID 25416956)
  • Data Source: BioGRID (two hybrid)

OLFM4

SYNE4

Name olfactomedin 4 spectrin repeat containing nuclear envelope family member 4
Structure No pdb structure PDB 6R16
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways None
GWAS
  • Adult body size ( 32376654 )
  • Adventurousness ( 30643258 )
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757 )
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028 )
  • BMI (adjusted for smoking behaviour) ( 28443625 )
  • BMI in non-smokers ( 28443625 )
  • Body mass index ( 29381148 24861553 25673413 25953783 28448500 26961502 )
  • Body mass index (joint analysis main effects and physical activity interaction) ( 28448500 )
  • Body mass index (joint analysis main effects and smoking interaction) ( 28443625 )
  • Body size at age 10 ( 32376654 )
  • Cerebrospinal P-tau181p levels ( 28247064 )
  • Childhood body mass index ( 26604143 )
  • Depression ( 29700475 )
  • Hip circumference ( 25673412 )
  • Immune response to anthrax vaccine ( 22658931 )
  • Intelligence (MTAG) ( 29326435 )
  • Major depressive disorder ( 27479909 )
  • Multisite chronic pain ( 33830993 )
  • Obesity ( 23563607 22484627 )
  • Obesity-related traits ( 23251661 )
  • Waist circumference ( 25673412 )
No GWAS studies recorded
Interacting Genes 36 interacting genes: APP AQP2 AQP3 BSCL2 C3 CFTR CLDN7 CLEC17A CLEC7A CLSTN3 CLTRN CREB3L1 EREG FAM209A FNDC9 IL11RA ITM2C KASH5 KIR2DL3 KIR3DL3 LDLRAD1 LEUTX LHFPL2 PVR PVRIG QPCTL SAR1A SLC18A1 SLC22A23 SUSD3 SYNE4 TFR2 TMEM130 TNFSF11 TNFSF14 TSPAN18 56 interacting genes: ABT1 ADIPOQ BRICD5 C3orf52 CD47 CEP19 CFTR CLDN19 CLDN7 CLDN8 CLEC7A CMTM5 CSNK2B CXCL9 DEFB121 ECE2 EDDM3B EMP1 ENTPD3 FAM241B FATE1 GADD45A GSK3B IGFBP5 ITM2B KLHL12 KLRG1 KTN1 MALL MARCHF2 NAGK OCLN OLFM4 OSTCP1 PAQR5 PLPP6 RIPPLY2 RPS6KA6 SEC22A SEC23B SENP2 SFTPC SLN SMCO4 TCEA2 TMEM115 TMEM140 TMEM147 TMEM182 TMEM248 TMPRSS4 TRIM69 TSPAN15 VTI1B ZNF250 ZNF648
Entrez ID 10562 163183
HPRD ID 06580 08776
Ensembl ID ENSG00000102837 ENSG00000181392
Uniprot IDs Q6UX06 Q8N205
PDB IDs Not available 6R16 6WMD
GO Terms Enriched among Interactors