RPP30 and RPP38

Number of citations: 33 (PubMedID 9630247)
Data Source: HPRD (in vivo)

		RPP30	RPP38
Name		ribonuclease P/MRP subunit p30	ribonuclease P/MRP subunit p38
Structure
GO Annotations	Cellular Component	Ribonuclease MRP Complex Nucleus Nucleoplasm Nucleolar Ribonuclease P Complex Nucleolus Multimeric Ribonuclease P Complex	Ribonuclease MRP Complex Fibrillar Center Nucleus Nucleoplasm Nucleolar Ribonuclease P Complex Nucleolus Multimeric Ribonuclease P Complex
	Molecular Function	RNA Binding Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding	RNA Binding Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding
	Biological Process	TRNA 5'-leader Removal RRNA Processing TRNA Processing	TRNA 5'-leader Removal RRNA Processing TRNA Processing
Pathways		tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol	tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol
GWAS		Economic and political preferences (time) ( 22566634 ) Metabolite levels ( 23823483 )	Clozapine-induced agranulocytosis ( 25187353 ) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309 )
Interacting Genes		14 interacting genes: CEBPA HMG20A KHDRBS2 MAST1 POP1 POP4 PTEN RNF32 RPP14 RPP21 RPP38 RPP40 UBC WEE2-AS1	9 interacting genes: POP1 POP4 POP7 PTEN RPP14 RPP21 RPP25 RPP30 RPP40
Entrez ID		10556	10557
HPRD ID		09359	09360
Ensembl ID		ENSG00000148688	ENSG00000152464
Uniprot IDs		P78346	P78345
PDB IDs		6AHR 6AHU	6AHR 6AHU
GO Terms Enriched among Interactors		Ribonuclease P RNA Binding Multimeric Ribonuclease P Complex Ribonuclease P Activity TRNA 5'-leader Removal TRNA 5'-end Processing Nucleolar Ribonuclease P Complex Ribonuclease MRP Complex TRNA Processing Ribonuclease P Complex TRNA Metabolic Process RNA Processing Endoribonuclease Complex Nucleolus RNA Metabolic Process RNA Binding Nucleic Acid Metabolic Process Nucleoplasm Macromolecule Metabolic Process Nucleobase-containing Compound Metabolic Process RRNA Processing RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Negative Regulation Of Synaptic Vesicle Clustering Ribonuclease MRP Activity RRNA Metabolic Process Response To Vitamin B2 C/EBP Complex Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity	Ribonuclease P RNA Binding Multimeric Ribonuclease P Complex Ribonuclease P Activity TRNA 5'-leader Removal TRNA 5'-end Processing Ribonuclease MRP Complex TRNA Processing Nucleolar Ribonuclease P Complex TRNA Metabolic Process RNA Processing Ribonuclease P Complex Nucleolus RNA Metabolic Process RNA Binding RRNA Processing RRNA Metabolic Process Nucleic Acid Metabolic Process Endoribonuclease Complex Nucleoplasm Nucleobase-containing Compound Metabolic Process Macromolecule Metabolic Process Nucleus Negative Regulation Of Synaptic Vesicle Clustering Ribonuclease MRP Activity Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Phosphatidylinositol Phosphate Phosphatase Activity Regulation Of Synaptic Vesicle Clustering Negative Regulation Of Peptidyl-serine Phosphorylation Postsynaptic Density Assembly Neuron-neuron Synaptic Transmission Negative Regulation Of Cell Size Anaphase-promoting Complex Binding Forebrain Morphogenesis Presynaptic Membrane Assembly Presynaptic Membrane Organization Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Postsynaptic Specialization Assembly Schmidt-Lanterman Incisure Negative Regulation Of Excitatory Postsynaptic Potential TRNA Decay Locomotor Rhythm Cellular Response To Electrical Stimulus