PPIE and PHYHIP

Number of citations: 0 (PubMedID 16169070)
Data Source: BioGRID (two hybrid), HPRD (two hybrid)

		PPIE	PHYHIP
Name		peptidylprolyl isomerase E	phytanoyl-CoA 2-hydroxylase interacting protein
Structure			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cytosol Nuclear Speck Protein-containing Complex Secretory Granule Lumen Intracellular Membrane-bounded Organelle U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome Ficolin-1-rich Granule Lumen	Cytoplasm
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Poly(A) Binding Cyclosporin A Binding Isomerase Activity	Protein Binding Protein Tyrosine Kinase Binding
	Biological Process	MRNA Splicing, Via Spliceosome Regulation Of DNA-templated Transcription MRNA Processing Protein Folding RNA Splicing Positive Regulation Of Viral Genome Replication	Intracellular Protein Localization
Pathways		Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER Neutrophil degranulation mRNA Splicing - Major Pathway	None
GWAS		Blood protein levels ( 30072576 )	Hypertriglyceridemia ( 23505323 )
Interacting Genes		11 interacting genes: GTSE1 KMT2A PCM1 PHYHIP PRC1 PRPF6 SLU7 SUMO2 TRIM55 TRIM63 XAB2	24 interacting genes: ADGRB1 COPS6 DYRK1A EEF1A1 ERG28 FAM131A HDAC11 HNRNPA1 MAGED4B MED8 METTL18 NDRG1 NDUFV3 NFE2 PHYH PNPLA2 PPIE PRMT5 S100A13 SMARCC2 SUPT5H TTR WDR89 ZZEF1
Entrez ID		10450	9796
HPRD ID		03893	16345
Ensembl ID		ENSG00000084072	ENSG00000168490
Uniprot IDs		E9PK21 Q9UNP9	Q92561
PDB IDs		1ZMF 2CQB 2KU7 2KYX 2R99 3LPY 3MDF 3UCH 5MQF 5YZG 5Z56 5Z57 6FF7 6ICZ 6ID0 6ID1 7A5P 7ABI 7W59 7W5A 7W5B 7ZEV 7ZEW 7ZEX 7ZEY 7ZEZ 8C6J 8CH6 8I0P 8I0R 8I0S 8I0T 8I0U 8I0V 8I0W 9FMD	Not available
GO Terms Enriched among Interactors		Catalytic Step 2 Spliceosome Microtubule MRNA Splicing, Via Spliceosome Spliceosomal Complex Protein-RNA Complex Assembly RNA Splicing, Via Transesterification Reactions Microtubule Cytoskeleton Second Spliceosomal Transesterification Activity Negative Regulation Of DNA Methylation-dependent Heterochromatin Formation Protein-cysteine Methyltransferase Activity Protein-containing Complex Localization To Centriolar Satellite Mitotic Spindle Elongation Generation Of Catalytic Spliceosome For First Transesterification Step Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Nucleoplasm	None