ABCC5 and RBP5

Number of citations: 38 (PubMedID 21988832)
Data Source: BioGRID (two hybrid)

		ABCC5	RBP5
Name		ATP binding cassette subfamily C member 5	retinol binding protein 5
Structure
GO Annotations	Cellular Component	Endosome Golgi Apparatus Golgi Lumen Plasma Membrane Endosome Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane	Nucleus Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Nucleotide Binding ATP Binding Organic Anion Transmembrane Transporter Activity ABC-type Xenobiotic Transporter Activity Purine Nucleotide Transmembrane Transporter Activity Heme Transmembrane Transporter Activity Efflux Transmembrane Transporter Activity ATP Hydrolysis Activity Macromolecule Transmembrane Transporter Activity Glutathione Transmembrane Transporter Activity ATPase-coupled Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity ATPase-coupled Inorganic Anion Transmembrane Transporter Activity ABC-type Transporter Activity Carbohydrate Derivative Transmembrane Transporter Activity	Retinoid Binding Fatty Acid Binding Protein Binding Lipid Binding Retinal Binding Retinol Binding
	Biological Process	Xenobiotic Metabolic Process Xenobiotic Transmembrane Transport Purine Nucleotide Transport Hyaluronan Biosynthetic Process Glutathione Transmembrane Transport Heme Transmembrane Transport Xenobiotic Transport Transmembrane Transport CAMP Transport CGMP Transport Monoatomic Anion Transmembrane Transport Folate Transmembrane Transport Export Across Plasma Membrane Transport Across Blood-brain Barrier Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane	Fatty Acid Transport
Pathways		Hyaluronan metabolism ABC-family proteins mediated transport Azathioprine ADME Paracetamol ADME	None
Drugs		Curcumin Curcumin sulfate	None
GWAS		Anterior chamber depth ( 24603532 ) Basophil percentage of white cells ( 32888494 ) Eosinophil count ( 32888494 ) Mean corpuscular hemoglobin concentration ( 32888494 ) Monocyte percentage of white cells ( 32888494 ) Neutrophil count ( 32888494 ) Platelet count ( 27863252 32888494 ) Platelet distribution width ( 32888494 ) Plateletcrit ( 32888494 ) Red cell distribution width ( 32888494 ) Type 2 diabetes ( 30297969 ) White blood cell count ( 32888494 )	Night sleep phenotypes ( 27126917 ) Plateletcrit ( 32888494 ) Refractive error ( 32231278 )
Interacting Genes		5 interacting genes: AK2 RBP5 SERPINA3 SMC2 TIAM1	5 interacting genes: ABCC5 AGR2 CCNDBP1 H3-4 NR0B2
Entrez ID		10057	83758
HPRD ID		06898	17961
Ensembl ID		ENSG00000114770	ENSG00000139194
Uniprot IDs		O15440	P82980
PDB IDs		8KCI 8WI2 8WI3 8WI4 8WI5	1GGL 6E5W 9BCB
GO Terms Enriched among Interactors		Extracellular Exosome ADP Biosynthetic Process Nucleobase-containing Small Molecule Interconversion Nucleoside Monophosphate Phosphorylation Sperm Mitochondrial Sheath Nucleobase-containing Compound Kinase Activity Phosphotransferase Activity, Phosphate Group As Acceptor AMP Kinase Activity Condensin Complex Meiotic Chromosome Condensation Positive Regulation Of Chromosome Condensation Nucleoside Diphosphate Biosynthetic Process Ribonucleoside Diphosphate Biosynthetic Process Lipid Binding Regulation Of Dopaminergic Neuron Differentiation Meiotic Chromosome Segregation Regulation Of Chromosome Condensation Retinol Binding Retinal Binding Retinoid Binding Mitotic Chromosome Condensation Kinetochore Organization	Carbohydrate Derivative Transmembrane Transporter Activity CGMP Transport Macromolecule Transmembrane Transporter Activity Spermatogonial Cell Division Hyaluronan Biosynthetic Process Heme Transmembrane Transport Folate Transmembrane Transport Purine Nucleotide Transmembrane Transporter Activity CAMP Transport Lung Goblet Cell Differentiation Positive Regulation Of PERK-mediated Unfolded Protein Response DNA Replication-dependent Chromatin Assembly Peroxisome Proliferator Activated Receptor Binding Folic Acid Transport Cyclic Nucleotide Transport Glutathione Transmembrane Transporter Activity Heme Transmembrane Transporter Activity Efflux Transmembrane Transporter Activity Glutathione Transport Glutathione Transmembrane Transport Heme Transport Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Dystroglycan Binding Positive Regulation Of IRE1-mediated Unfolded Protein Response Nuclear Retinoid X Receptor Binding Nuclear Retinoic Acid Receptor Binding Oligopeptide Transport Xenobiotic Export From Cell ABC-type Xenobiotic Transporter Activity Iron Ion Transmembrane Transport Oligopeptide Transmembrane Transport Glycosaminoglycan Biosynthetic Process Xenobiotic Transmembrane Transport Vitamin Transmembrane Transport Positive Regulation Of Endoplasmic Reticulum Unfolded Protein Response Regulation Of IRE1-mediated Unfolded Protein Response Regulation Of PERK-mediated Unfolded Protein Response Mucus Secretion Organic Anion Transmembrane Transporter Activity Positive Regulation Of Protein Localization Digestive Tract Morphogenesis Xenobiotic Transmembrane Transporter Activity Hyaluronan Metabolic Process Lung Epithelial Cell Differentiation Lung Cell Differentiation Nuclear Thyroid Hormone Receptor Binding ATPase-coupled Transmembrane Transporter Activity Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Adenine Nucleotide Transport