CDH7 and CDH15

Number of citations: 34 (PubMedID 10861224)
Data Source: HPRD (in vivo)

		CDH7	CDH15
Name		cadherin 7	cadherin 15
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Adherens Junction Membrane Catenin Complex	Golgi Apparatus Plasma Membrane Caveola Adherens Junction Membrane Catenin Complex Neuromuscular Junction Extracellular Exosome
	Molecular Function	Calcium Ion Binding Beta-catenin Binding Cadherin Binding Metal Ion Binding	Calcium Ion Binding Protein Binding Beta-catenin Binding Cadherin Binding Metal Ion Binding
	Biological Process	Cell Morphogenesis Cell-cell Junction Assembly Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cell Migration Adherens Junction Organization Cell-cell Adhesion Mediated By Cadherin Cell-cell Adhesion	Cell Morphogenesis Cell-cell Junction Assembly Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cell Migration Adherens Junction Organization Cell-cell Adhesion Mediated By Cadherin Cell-cell Adhesion
Pathways		Adherens junctions interactions	Adherens junctions interactions Myogenesis Myogenesis
Diseases		None	Non-syndromic autosomal dominant mental retardation
GWAS		Adult body size ( 32376654 ) Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU) ( 24025145 ) Body mass index ( 28892062 ) Cardiac Troponin-T levels ( 23247143 ) Fractional excretion of metabolites in chronic kidney disease ( 29545352 ) Glucagon levels in response to oral glucose tolerance test (decremental area under the curve for 0-30 minutes) ( 33407418 ) Irritable mood ( 29500382 ) Metabolite levels ( 23823483 ) Prudent dietary pattern ( 28644415 )	No GWAS studies recorded
Interacting Genes		6 interacting genes: CDH12 CDH15 CDH6 CDH9 CTNNB1 FGF21	12 interacting genes: ARVCF BOC CDH7 CDH9 CDON CTNNA1 CTNNB1 GNA12 JUP SGTA SGTB UBQLN2
Entrez ID		1005	1013
HPRD ID		12049	00225
Ensembl ID		ENSG00000081138	ENSG00000129910
Uniprot IDs		F5H5X9 Q8IY78 Q9ULB5	P55291
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Catenin Complex Cell-cell Adhesion Mediated By Cadherin Adherens Junction Organization Cell-cell Junction Assembly Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cell-cell Junction Organization Cell Morphogenesis Adherens Junction Cell Junction Assembly Cadherin Binding Beta-catenin Binding Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cell Junction Organization Cell-cell Adhesion Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell Adhesion Cell Migration Cell Motility Calcium Ion Binding Anatomical Structure Morphogenesis Synaptic Membrane Adhesion Fibroblast Growth Factor Receptor Signaling Pathway Cellular Component Assembly Glial Cell Fate Determination Canonical Wnt Signaling Pathway Involved In Mesenchymal Stem Cell Differentiation Developmental Process Mesenchymal Stem Cell Differentiation Positive Regulation Of Determination Of Dorsal Identity Negative Regulation Of Mitotic Cell Cycle, Embryonic Beta-catenin-ICAT Complex Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Renal Inner Medulla Development Scrib-APC-beta-catenin Complex Renal Outer Medulla Development Renal Vesicle Formation Positive Regulation Of Branching Involved In Lung Morphogenesis Neural Plate Development Oviduct Development Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Fungiform Papilla Formation Beta-catenin-TCF7L2 Complex Astrocyte-dopaminergic Neuron Signaling Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Regulation Of Centriole-centriole Cohesion Embryonic Skeletal Limb Joint Morphogenesis Lung Induction Catenin-TCF7L2 Complex Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Negative Regulation Of Epithelial Cell Differentiation Involved In Kidney Development Acinar Cell Differentiation	Catenin Complex Cell-cell Adhesion Adherens Junction Cellular Response To Indole-3-methanol Response To Indole-3-methanol Cell-cell Junction Assembly Cell Adhesion Cadherin Binding Cell-cell Junction Organization TRC Complex Cell Junction Assembly Catenin-TCF7L2 Complex Cell-cell Adhesion Mediated By Cadherin Regulation Of Neuroblast Proliferation Neuroblast Proliferation Intercalated Disc Adherens Junction Organization Cell Junction Organization Zonula Adherens Flotillin Complex Alpha-catenin Binding Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Regulation Of Neural Precursor Cell Proliferation Neural Precursor Cell Proliferation Beta-catenin Binding Plasma Membrane Epithelial Cell-cell Adhesion Positive Regulation Of ERAD Pathway Positive Regulation Of Skeletal Muscle Tissue Development Positive Regulation Of Striated Muscle Tissue Development Anchoring Junction Regulation Of Skeletal Muscle Tissue Development Regulation Of ERAD Pathway Focal Adhesion Positive Regulation Of Neuroblast Proliferation Protein Targeting To ER Cell Migration Anatomical Structure Morphogenesis Establishment Of Protein Localization To Endoplasmic Reticulum Cell Morphogenesis Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Membrane Cell-cell Junction Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Striated Muscle Tissue Development Cellular Component Assembly Detection Of Mechanical Stimulus Regulation Of Muscle Organ Development Protein-DNA Complex