ACTR8

Name	actin related protein 8
Structure
Interactors	2 interactors: BMPR2 HUNK
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Centrosome Ino80 Complex
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding
	Biological Process	Telomere Maintenance Regulation Of DNA Replication DNA Repair Regulation Of DNA Repair Double-strand Break Repair DNA Recombination Chromatin Remodeling Regulation Of DNA-templated Transcription DNA Damage Response Positive Regulation Of Macromolecule Metabolic Process Regulation Of Chromosome Organization Positive Regulation Of DNA Repair Positive Regulation Of DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Embryonic Development Regulation Of DNA Metabolic Process Cell Division Regulation Of Cell Cycle Regulation Of DNA Strand Elongation Positive Regulation Of Telomere Maintenance In Response To DNA Damage
Pathways	UCH proteinases DNA Damage Recognition in GG-NER
GWAS	Axial length ( 24144296 ) Body mass index ( 26426971 )
Entrez ID	93973
HPRD ID	09792
Ensembl ID	ENSG00000113812
Uniprot IDs	Q9H981
PDB IDs	4FO0
GO Terms Enriched among Interactors ?	Positive Regulation Of Axon Extension Involved In Axon Guidance Negative Regulation Of Chondrocyte Proliferation Regulation Of Lung Blood Pressure Aortic Valve Development Protein Kinase Activity Protein Serine/threonine Kinase Activity Lymphatic Endothelial Cell Differentiation BMP Receptor Activity Pulmonary Valve Development Tricuspid Valve Morphogenesis Venous Blood Vessel Development Negative Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Negative Regulation Of Cell Proliferation Involved In Heart Morphogenesis Activin Receptor Activity, Type II Endochondral Bone Morphogenesis Transforming Growth Factor Beta Receptor Activity Semi-lunar Valve Development Mitral Valve Morphogenesis Maternal Placenta Development Lung Vasculature Development Kinase Activity Pharyngeal Arch Artery Morphogenesis Endothelial Cell Apoptotic Process Transmembrane Receptor Protein Serine/threonine Kinase Activity Negative Regulation Of Vasoconstriction Endocardial Cushion Development Lymphangiogenesis Regulation Of Axon Extension Involved In Axon Guidance Retina Vasculature Development In Camera-type Eye Atrial Septum Morphogenesis Regulation Of Cell Proliferation Involved In Heart Morphogenesis Atrioventricular Valve Morphogenesis BMP Binding Negative Regulation Of Systemic Arterial Blood Pressure Heart Valve Development Chondrocyte Development Outflow Tract Septum Morphogenesis Endothelial Cell Differentiation Activin Receptor Signaling Pathway Cellular Response To BMP Stimulus Positive Regulation Of Cartilage Development Maternal Process Involved In Female Pregnancy Bone Morphogenesis Organelle Endothelial Cell Proliferation Positive Regulation Of Axon Extension Ventricular Septum Morphogenesis Positive Regulation Of SMAD Protein Signal Transduction Protein Tyrosine Kinase Binding Positive Regulation Of Bone Mineralization