MVB12B

Description		multivesicular body subunit 12B
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GO Annotations	Cellular Component	ESCRT I Complex Nucleus Cytoplasm Endosome Early Endosome Late Endosome Cytosol Plasma Membrane Endosome Membrane Membrane Late Endosome Membrane Vesicle Extracellular Exosome
	Molecular Function	Protein Binding Lipid Binding Ubiquitin Binding
	Biological Process	Protein Transport Virus Maturation Multivesicular Body Assembly Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Viral Budding Membrane Fission
Pathways		Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Appendicular lean mass ( 33097823) Bipolar disorder ( 31043756) Calcium levels ( 29403010) Chin dimples ( 27182965) Eyebrow thickness ( 26926045) Malaria ( 31844061) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		1 interacting genes: LNX1
Entrez ID		89853
HPRD ID		12952
Ensembl ID		ENSG00000196814
Uniprot IDs		Q9H7P6
PDB IDs		3TOW
Enriched GO Terms of Interacting Partners?		Synapse Maturation
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