TSEN2

Name	tRNA splicing endonuclease subunit 2
Structure
Novel Interactors	1 novel interactors: NUP210
Interactors	7 interactors: CADPS CTAG2 GABPB2 RANBP10 TAX1BP1 TEPSIN TSEN54
GO Annotations	Cellular Component	TRNA-intron Endonuclease Complex Nucleus Nucleoplasm Nucleolus Cytoplasm Centrosome Cytosol
	Molecular Function	TRNA-intron Lyase Activity Nucleic Acid Binding Protein Binding Lyase Activity
	Biological Process	TRNA-type Intron Splice Site Recognition And Cleavage TRNA Splicing, Via Endonucleolytic Cleavage And Ligation MRNA Processing TRNA Processing
Pathways	tRNA processing in the nucleus
Diseases	Pontocerebellar hypoplasia
GWAS	A body shape index ( 34021172 ) Hip circumference adjusted for BMI ( 34021172 ) Hip index ( 34021172 ) Systemic lupus erythematosus ( 28714469 ) Waist circumference adjusted for body mass index ( 34021172 ) Waist-hip index ( 34021172 ) Waist-to-hip ratio adjusted for BMI ( 26426971 34021172 ) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971 ) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971 ) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971 )
Entrez ID	80746
HPRD ID	10576
Ensembl ID	ENSG00000154743
Uniprot IDs	A0A7P0T8F8 A0A7P0T914 A0A7P0TA86 C9J7Z4 Q8NCE0
PDB IDs	7UXA 7ZRZ 8HMY 8HMZ 8ISS