ST7

Name	suppression of tumorigenicity 7
Structure	No pdb structure
Interactors	9 interactors: ACTN2 CUL4A CUL4B DCAF4 MYOT NFKBIA RACK1 SNAPIN ZFYVE9
GO Annotations	Cellular Component	Membrane
	Molecular Function	Protein Binding
	Biological Process	Extracellular Matrix Organization Regulation Of Cell Differentiation
GWAS	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098 ) Intraocular pressure ( 30591961 ) Response to alcohol consumption (flushing response) ( 29460428 ) Response to platinum-based chemotherapy in non-small-cell lung cancer ( 22872573 ) Waist-to-hip ratio adjusted for BMI ( 26426971 ) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971 )
Entrez ID	7982
HPRD ID	09015
Ensembl ID	ENSG00000004866
Uniprot IDs	B7Z4L1 B7Z4U3 E7EPD9 E7EPW5 G3XAH9 H7BXS2 Q9NRC1 X5DRA0
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Cul4-RING E3 Ubiquitin Ligase Complex Cul4A-RING E3 Ubiquitin Ligase Complex Cullin-RING Ubiquitin Ligase Complex Regulation Of Cellular Localization Positive Regulation Of Protein Catabolic Process Protein Ubiquitination Structural Constituent Of Muscle Regulation Of Intracellular Transport Protein Modification By Small Protein Conjugation Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Actin Filament Uncapping Ubiquitin Protein Ligase Binding Positive Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Late Endosome To Lysosome Transport Post-translational Protein Modification Titin Z Domain Binding Negative Regulation Of Transport Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Mitotic Cell Cycle Phase Transition Cellular Response To UV Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Regulation Of Protein Catabolic Process IRE1-RACK1-PP2A Complex Negative Regulation Of Translational Frameshifting Phospholipase C-activating Angiotensin-activated Signaling Pathway I-kappaB/NF-kappaB Complex Positive Regulation Of Cell Cycle Phase Transition Cellular Response To Light Stimulus Ribosome Biogenesis Positive Regulation Of Mitotic Cell Cycle Microspike Assembly Z Disc Positive Regulation Of Intracellular Transport FATZ Binding Regulation Of Vesicle-mediated Transport Mitotic Cell Cycle Phase Transition Positive Regulation Of Catabolic Process Base-excision Repair, AP Site Formation Via Deaminated Base Removal Negative Regulation Of Translational Elongation Terminal Button Organization Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Response To UV Cell Cycle Phase Transition Cul4B-RING E3 Ubiquitin Ligase Complex Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Golgi To Plasma Membrane Protein Transport BH3 Domain Binding