ENGASE

Name	endo-beta-N-acetylglucosaminidase
Structure	No pdb structure
Interactors	1 interactors: ZP3
GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Hydrolase Activity Hydrolase Activity, Acting On Glycosyl Bonds Mannosyl-glycoprotein Endo-beta-N-acetylglucosaminidase Activity
	Biological Process	Protein Folding N-glycan Processing
Pathways	N-glycan trimming in the ER and Calnexin/Calreticulin cycle
GWAS	No GWAS studies recorded
Entrez ID	64772
HPRD ID	10978
Ensembl ID	ENSG00000167280
Uniprot IDs	Q8NFI3
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Positive Regulation Of Acrosomal Vesicle Exocytosis Positive Regulation Of Ovarian Follicle Development Positive Regulation Of Type IV Hypersensitivity Egg Coat Formation Acrosin Binding Positive Regulation Of Antral Ovarian Follicle Growth Negative Regulation Of Binding Of Sperm To Zona Pellucida Structural Constituent Of Egg Coat Egg Coat Regulation Of Type IV Hypersensitivity Regulation Of Acrosomal Vesicle Exocytosis Regulation Of Binding Of Sperm To Zona Pellucida Humoral Immune Response Mediated By Circulating Immunoglobulin Regulation Of Ovarian Follicle Development Positive Regulation Of Hypersensitivity Positive Regulation Of Acute Inflammatory Response To Antigenic Stimulus Positive Regulation Of Acrosome Reaction Positive Regulation Of Inflammatory Response To Antigenic Stimulus Regulation Of Acrosome Reaction Oocyte Development Positive Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Acute Inflammatory Response To Antigenic Stimulus Positive Regulation Of Humoral Immune Response Blastocyst Formation Positive Regulation Of Acute Inflammatory Response Positive Regulation Of Interleukin-4 Production Binding Of Sperm To Zona Pellucida Regulation Of Interleukin-4 Production Immunoglobulin Mediated Immune Response Regulation Of Calcium Ion-dependent Exocytosis Sperm-egg Recognition Positive Regulation Of Regulated Secretory Pathway B Cell Mediated Immunity Regulation Of Humoral Immune Response Regulation Of Acute Inflammatory Response Cell-cell Recognition Negative Regulation Of Reproductive Process Positive Regulation Of T Cell Mediated Immunity Positive Regulation Of Type II Interferon Production Positive Regulation Of Reproductive Process Positive Regulation Of Exocytosis Single Fertilization Regulation Of T Cell Mediated Immunity Positive Regulation Of T Cell Proliferation Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Cell Recognition Receptor Ligand Activity Positive Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Regulation Of Type II Interferon Production Positive Regulation Of Lymphocyte Mediated Immunity