MYO5C

Name	myosin VC
Structure
Novel Interactors	1 novel interactors: FBN1
Interactors	4 interactors: CRYAA IKBKG POT1 RAB8A
GO Annotations	Cellular Component	Cytoplasm Actin Cytoskeleton Membrane Myosin Complex Extracellular Exosome Schaffer Collateral - CA1 Synapse
	Molecular Function	Microfilament Motor Activity Nucleotide Binding Cytoskeletal Motor Activity Actin Binding Calmodulin Binding ATP Binding Actin Filament Binding
	Biological Process	Endocytosis Actin Filament Organization Vesicle Transport Along Actin Filament
GWAS	Glucose homeostasis traits ( 25524916 ) Hip circumference adjusted for BMI ( 28552196 ) Systemic lupus erythematosus ( 32771030 ) Type 2 diabetes ( 32499647 )
Entrez ID	55930
HPRD ID	11380
Ensembl ID	ENSG00000128833
Uniprot IDs	Q9NQX4
PDB IDs	4L8T 4ZG4 5HMP
GO Terms Enriched among Interactors ?	Embryonic Eye Morphogenesis Eye Morphogenesis Sensory Organ Morphogenesis Camera-type Eye Development Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Embryonic Organ Morphogenesis Eye Development Sensory Organ Development Cellular Response To Peptide Hormone Stimulus Sequestering Of BMP In Extracellular Matrix Positive Regulation Of Response To Food Sequestering Of TGFbeta In Extracellular Matrix Positive Regulation Of Appetite Activation Of Protein Kinase A Activity Golgi Vesicle Fusion To Target Membrane Linear Polyubiquitin Binding Positive Regulation Of Telomeric Loop Disassembly 8-hydroxy-2'-deoxyguanosine DNA Binding Telomeric G-quadruplex DNA Binding Telomeric D-loop Binding Telomere Assembly Negative Regulation Of Osteoclast Development Single-stranded Telomeric DNA Binding Cellular Component Assembly Shelterin Complex Lens Fiber Cell Morphogenesis Post-embryonic Eye Morphogenesis IkappaB Kinase Complex Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere Tubulin Complex Assembly Sequestering Of Extracellular Ligand From Receptor Extracellular Negative Regulation Of Signal Transduction Response To Peptide Hormone Regulation Of Osteoclast Development Cellular Response To Insulin-like Growth Factor Stimulus Extracellular Matrix Constituent Conferring Elasticity Establishment Of Protein Localization To Postsynaptic Membrane Neurotransmitter Receptor Transport To Postsynaptic Membrane Neurotransmitter Receptor Transport To Plasma Membrane Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport, Endosome To Plasma Membrane Transferrin Receptor Binding Nuclear Telomere Cap Complex Telomeric Loop Disassembly Telomeric D-loop Disassembly DEAD/H-box RNA Helicase Binding G-rich Strand Telomeric DNA Binding