RAB4B

Name	RAB4B, member RAS oncogene family
Structure
Interactors	9 interactors: BOLA2 BOLA2B CDC45 EXOC5 GARIN6 RAB7A RABAC1 RABEP1 VPS52
GO Annotations	Cellular Component	Endosome Cytosol Plasma Membrane Membrane Cytoplasmic Vesicle Membrane Secretory Granule Membrane Early Endosome Membrane Insulin-responsive Compartment Perinuclear Region Of Cytoplasm Recycling Endosome
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Protein Transport Vesicle-mediated Transport Regulation Of Endocytosis Rab Protein Signal Transduction Endosomal Vesicle Fusion Early Endosome To Golgi Transport D-glucose Import
Pathways	Neutrophil degranulation RAB geranylgeranylation MET receptor recycling
GWAS	Carotid intima media thickness (mean) ( 31801372 ) Chronic obstructive pulmonary disease ( 22080838 28166215 ) Emphysema imaging phenotypes ( 26030696 ) Eosinophil percentage of white cells ( 32888494 ) Hematocrit ( 32888494 ) Hemoglobin ( 32888494 ) Kawasaki disease ( 22081228 ) Red blood cell count ( 32888494 ) Smoking behaviour (cigarettes smoked per day) ( 30617275 )
Entrez ID	53916
HPRD ID	11473
Ensembl ID	ENSG00000167578
Uniprot IDs	P61018
PDB IDs	2O52
GO Terms Enriched among Interactors ?	Vesicle-mediated Transport To The Plasma Membrane Post-Golgi Vesicle-mediated Transport Iron-sulfur Cluster Assembly Complex [2Fe-2S] Cluster Assembly Iron-sulfur Cluster Assembly 2 Iron, 2 Sulfur Cluster Binding Localization Within Membrane Protein Localization To Cell Periphery Cell Redox Homeostasis Golgi Vesicle Transport Embryonic Ectodermal Digestive Tract Development Synaptic Vesicle Recycling Via Endosome Protein Localization To Membrane Mitotic DNA Replication Preinitiation Complex Assembly Golgi To Plasma Membrane Transport Intracellular Iron Ion Homeostasis Iron-sulfur Cluster Binding Endocytic Recycling Negative Regulation Of Intralumenal Vesicle Formation Membrane Docking Epidermal Growth Factor Catabolic Process Intracellular Monoatomic Ion Homeostasis Neurotransmitter Receptor Transport, Postsynaptic Endosome To Lysosome Intracellular Monoatomic Cation Homeostasis DNA Replication Preinitiation Complex Retrograde Transport, Endosome To Golgi Protein Transport Monoatomic Cation Homeostasis Lipophagy DNA Replication Preinitiation Complex Assembly Monoatomic Ion Homeostasis Lysosomal Transport Cytosolic Transport Vesicle-mediated Transport Negative Regulation Of Exosomal Secretion Intracellular Chemical Homeostasis Recycling Endosome GARP Complex EARP Complex Ectodermal Cell Differentiation Protein To Membrane Docking Glutamatergic Synapse Regulation Of Endosome Organization Membrane Fusion Establishment Of Protein Localization Alveolar Lamellar Body Vacuolar Transport Cellular Homeostasis Phagosome Acidification Membrane Organization