C9orf78

Name	chromosome 9 open reading frame 78
Structure
Novel Interactors	1 novel interactors: PTGES2
Interactors	6 interactors: APP FCHSD2 MAPK11 SMURF1 SUPT5H TAB1
GO Annotations	Cellular Component	Chromosome, Centromeric Region Nucleus Nucleoplasm Spliceosomal Complex Chromosome Cytosol
	Molecular Function	RNA Binding Protein Binding U5 SnRNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing Chromosome Segregation RNA Splicing MRNA Cis Splicing, Via Spliceosome Regulation Of Homologous Chromosome Segregation
Pathways	mRNA Splicing - Major Pathway
GWAS	No GWAS studies recorded
Entrez ID	51759
HPRD ID	10803
Ensembl ID	ENSG00000136819
Uniprot IDs	Q9NZ63
PDB IDs	7OS2 8C6J 9FMD
GO Terms Enriched among Interactors ?	Positive Regulation Of Macromolecule Metabolic Process Amyloid-beta Complex Positive Regulation Of Metabolic Process Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Regulation Of Developmental Growth Amylin Binding Positive Regulation Of Toll Signaling Pathway Clathrin-coated Pit Stereocilium Shaft Engulfment Of Target By Autophagosome Acetylcholine Receptor Activator Activity PTB Domain Binding Response To Interleukin-1 Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Catabolic Process Positive Regulation Of Cytokine Production Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Macromolecule Biosynthetic Process DSIF Complex 12-hydroxyheptadecatrienoic Acid Synthase Activity Prostaglandin-E Synthase Activity Regulation Of Growth Recycling Endosome Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Biosynthetic Process Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Supramolecular Fiber Organization Growth Factor Receptor Binding Main Axon Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Positive Regulation Of Multicellular Organismal Process Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway