CLEC4A

Name	C-type lectin domain family 4 member A
Structure
Novel Interactors	1 novel interactors: KAT8
Interactors	2 interactors: LMNA PTPN6
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Calcium Ion Binding D-mannose Binding Carbohydrate Binding Pattern Recognition Receptor Activity Metal Ion Binding
	Biological Process	Negative Regulation Of Cytokine Production Adaptive Immune Response Immune System Process Plasmacytoid Dendritic Cell Antigen Processing And Presentation Cell Adhesion Cell Surface Receptor Signaling Pathway Negative Regulation Of Tumor Necrosis Factor Production CD8-positive, Alpha-beta T Cell Activation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Innate Immune Response Antifungal Innate Immune Response
Pathways	Dectin-2 family
GWAS	No GWAS studies recorded
Entrez ID	50856
HPRD ID	05604
Ensembl ID	ENSG00000111729
Uniprot IDs	Q9UMR7
PDB IDs	5B1W 5B1X
GO Terms Enriched among Interactors ?	Nuclear Lumen DNA Double-strand Break Attachment To Nuclear Envelope Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Gene Expression Nuclear Matrix Cell Development Heterochromatin Formation Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Gene Expression Structural Constituent Of Nuclear Lamina Hemopoiesis Epididymis Development Positive Regulation Of Skeletal Muscle Satellite Cell Differentiation Protein Propionyltransferase Activity Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Lamin Filament Nuclear Pore Localization Epigenetic Regulation Of Gene Expression CD27 Signaling Pathway Myeloid Cell Differentiation Negative Regulation Of Mast Cell Activation Involved In Immune Response MSL Complex Post-embryonic Hemopoiesis Negative Regulation Of Macromolecule Biosynthetic Process Ventricular Cardiac Muscle Cell Development Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Mesenchymal Cell Proliferation Non-membrane Spanning Protein Tyrosine Phosphatase Activity Negative Regulation Of Neutrophil Activation Phosphorylation-dependent Protein Binding Negative Regulation Of Mast Cell Activation Inflammatory Response To Wounding Regulation Of Neutrophil Activation Negative Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Alpha-beta T Cell Receptor Complex Neutrophil Activation Involved In Immune Response Negative Regulation Of Cytokine Production Negative Regulation Of Inflammatory Response To Wounding Negative Regulation Of B Cell Receptor Signaling Pathway NSL Complex Skeletal Muscle Satellite Cell Differentiation Histone H4K8 Acetyltransferase Activity Histone H4K16 Acetyltransferase Activity Histone H4K5 Acetyltransferase Activity Positive Regulation Of Skeletal Muscle Cell Differentiation Regulation Of Mitochondrial Transcription Histone H4 Acetyltransferase Activity Nuclear Lamina Negative Regulation Of Biosynthetic Process Regulation Of Inflammatory Response To Wounding