IYD

Name	iodotyrosine deiodinase
Structure
Novel Interactors	1 novel interactors: SYNE1
Interactors	1 interactors: TRIM69
GO Annotations	Cellular Component	Nucleoplasm Plasma Membrane Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding FMN Binding Oxidoreductase Activity Iodotyrosine Deiodinase Activity
	Biological Process	Tyrosine Metabolic Process Thyroid Hormone Metabolic Process
Pathways	Thyroxine biosynthesis
Drugs	3,5-Diiodotyrosine
Diseases	Thyroid dyshormonogenesis; Dyshormogenetic goiter
GWAS	Anger ( 24489884 )
Entrez ID	389434
HPRD ID	16668
Ensembl ID	ENSG00000009765
Uniprot IDs	Q2VPV9 Q6PHW0
PDB IDs	4TTB 4TTC 5YAK
GO Terms Enriched among Interactors ?	Nuclear Matrix Organization Cytoskeleton-nuclear Membrane Anchor Activity Nuclear Matrix Anchoring At Nuclear Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex Centrosome Separation Lamin Binding Maintenance Of Protein Location In Nucleus Protein Localization To Centrosome Nuclear Outer Membrane Maintenance Of Protein Localization In Organelle Maintenance Of Protein Location In Cell Cytoskeleton Sarcomere Maintenance Of Protein Location Protein Localization To Cytoskeleton Centrosome Cycle Maintenance Of Location In Cell Nucleus Organization Maintenance Of Location Identical Protein Binding Microtubule Organizing Center Organization P-body Muscle Cell Differentiation