IDH3A

Name	isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha
Structure
Novel Interactors	1 novel interactors: ADAMTSL3
Interactors	7 interactors: IDH3B IDH3G MBNL1 PRPF6 RAB4A SF1 SUMO4
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Isocitrate Dehydrogenase Complex (NAD+)
	Molecular Function	Magnesium Ion Binding Isocitrate Dehydrogenase (NAD+) Activity Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Metal Ion Binding NAD Binding
	Biological Process	Carbohydrate Metabolic Process Tricarboxylic Acid Cycle Isocitrate Metabolic Process
Pathways	Citric acid cycle (TCA cycle) Mitochondrial protein degradation
Drugs	NADH Manganese Xanthinol Copper
GWAS	Eyebrow thickness ( 26926045 )
Entrez ID	3419
HPRD ID	03094
Ensembl ID	ENSG00000166411
Uniprot IDs	B4DJB4 B7Z9J8 P50213
PDB IDs	5GRE 5GRF 5GRH 5GRI 5GRL 5YVT 6KDE 6KDF 6KDY 6KE3 6L57 6L59 7CE3 8GRB 8GRD 8GRG 8GRH 8GRU 8GS5
GO Terms Enriched among Interactors ?	Isocitrate Dehydrogenase (NAD+) Activity Isocitrate Dehydrogenase Complex (NAD+) Isocitrate Metabolic Process Tricarboxylic Acid Metabolic Process Tricarboxylic Acid Cycle NAD Binding Spliceosomal Complex Assembly Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor RNA Splicing MRNA Processing Neurotransmitter Receptor Transport Postsynaptic Membrane To Endosome SUMO Ligase Complex MRNA Metabolic Process Insulin-responsive Compartment U2AF Complex MRNA 3'-splice Site Recognition Spliceosomal Complex Magnesium Ion Binding MRNA Splicing, Via Spliceosome Protein-RNA Complex Assembly RNA Splicing, Via Transesterification Reactions