CXCL2

Name	C-X-C motif chemokine ligand 2
Structure
Interactors	19 interactors: CCL11 CCL21 CCL28 CCL5 CCL8 CXCL11 CXCL12 CXCL14 CXCL5 CXCL6 CXCL9 CXCR1 CXCR2 EPS8 PF4 PIK3R1 PLG XCL1 XCL2
GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity
	Biological Process	Response To Molecule Of Bacterial Origin Chemotaxis Defense Response Inflammatory Response Immune Response Signal Transduction Killing Of Cells Of Another Organism Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Pathways	Chemokine receptors bind chemokines G alpha (i) signalling events Interleukin-10 signaling
GWAS	Basophil percentage of white cells ( 32888494 ) Eosinophil percentage of granulocytes ( 27863252 ) Granulocyte count ( 27863252 ) Granulocyte percentage of myeloid white cells ( 27863252 ) Inflammatory bowel disease ( 23128233 ) Lymphocyte percentage of white cells ( 27863252 32888494 ) Metabolite levels ( 23823483 ) Monocyte percentage of white cells ( 27863252 ) Myeloid white cell count ( 27863252 ) Neutrophil count ( 27863252 32888494 29403010 ) Neutrophil percentage of granulocytes ( 27863252 ) Neutrophil percentage of white cells ( 27863252 32888494 ) Sum basophil neutrophil counts ( 27863252 ) Sum neutrophil eosinophil counts ( 27863252 ) White blood cell count ( 32888494 29403010 27863252 21738479 ) White blood cell types ( 21738478 )
Entrez ID	2920
HPRD ID	00741
Ensembl ID	ENSG00000081041
Uniprot IDs	P19875
PDB IDs	1QNK 5OB5 8XVU 8XXH
GO Terms Enriched among Interactors ?	Chemokine Activity Leukocyte Migration Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Leukocyte Chemotaxis Chemotaxis Antimicrobial Humoral Response Cell Migration Locomotion Granulocyte Chemotaxis Chemokine-mediated Signaling Pathway Myeloid Leukocyte Migration Cell Motility Granulocyte Migration Cytokine Activity Humoral Immune Response Cytokine-mediated Signaling Pathway Immune System Process Immune Response Mononuclear Cell Migration Defense Response To Symbiont Defense Response To Other Organism Cell Killing Killing Of Cells Of Another Organism Neutrophil Chemotaxis Inflammatory Response CXCR Chemokine Receptor Binding Defense Response Neutrophil Migration Response To Other Organism Response To External Biotic Stimulus G Protein-coupled Receptor Signaling Pathway CCR Chemokine Receptor Binding Chemokine Receptor Binding Extracellular Space Dendritic Cell Migration Extracellular Region Signal Transduction Cell-cell Signaling Signaling Cell Communication Cell Surface Receptor Signaling Pathway Response To Stress Dendritic Cell Chemotaxis Positive Regulation Of Cell Migration Regulation Of Leukocyte Migration Positive Regulation Of Cell Motility Negative Regulation Of Leukocyte Tethering Or Rolling Positive Regulation Of Locomotion Eosinophil Chemotaxis