BSCL2

Name	BSCL2 lipid droplet biogenesis associated, seipin
Structure
Interactors	37 interactors: ANKRD46 B4GALNT2 BMP10 CLDN19 CMTM7 CPEB2 CXCL9 CYSRT1 ERMP1 GABARAPL1 GMCL1 HOXA1 KRTAP6-3 LAT MALL NSG1 OLFM4 PLEKHF2 PLIN1 RPRM SERP1 SERP2 SFTPC SMIM3 SMLR1 SPMIP9 STRIT1 TMEM19 TMEM218 TMEM222 TRAM1L1 TRARG1 TRIM54 TSPAN2 UPK2 USE1 VAMP3
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Membrane
	Molecular Function	Protein Binding Phospholipid Binding
	Biological Process	Lipid Metabolic Process Lipid Catabolic Process Lipid Storage Lipid Droplet Organization Fat Cell Differentiation Negative Regulation Of Lipid Catabolic Process Positive Regulation Of Cold-induced Thermogenesis Lipid Droplet Formation
Diseases	Congenital generalized lipodystrophy (CGL) Distal hereditary motor neuropathies (dHMN) Hereditary spastic paraplegia (SPG)
GWAS	Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482 ) Waist-to-hip ratio adjusted for BMI ( 26426971 ) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971 )
Entrez ID	26580
HPRD ID	05858
Ensembl ID	ENSG00000168000
Uniprot IDs	A0A024R549 J3KQ12 Q96G97
PDB IDs	6DS5