FRMD4B

Description		FERM domain containing 4B
Image		No pdb structure
GO Annotations	Cellular Component	Ruffle Extracellular Space Cytoplasm Cytoskeleton Adherens Junction Bicellular Tight Junction Anchoring Junction
	Molecular Function
	Biological Process	Establishment Of Epithelial Cell Polarity
Pathways
Drugs
Diseases
GWAS		Atrial fibrillation ( 30061737) Carotid intima media thickness x smoking interaction ( 32117412) Celiac disease ( 20190752 31591516) dexamethasone sensitivity in B-cell precursor acute lymphoblastic leukaemia ( 33002292) Fast beta electroencephalogram ( 28040410) Hepcidin/ferritin ratio ( 27846281) High myopia ( 32428537) PR interval ( 30046033 32439900) prednisolone sensitivity in B-cell precursor acute lymphoblastic leukaemia ( 33002292) Renal underexcretion gout ( 32238385) Resting heart rate ( 27798624) Resting-state electroencephalogram vigilance ( 29703947) Sphingomyelin 24:0 levels ( 31560688) Trunk fat mass ( 28552196)
Interacting Genes		2 interacting genes: CYTH3 RSPH1
Entrez ID		23150
HPRD ID		19415
Ensembl ID		ENSG00000114541
Uniprot IDs		B3KNA2 Q6PEW6 Q9Y2L6
PDB IDs
Enriched GO Terms of Interacting Partners?		Radial Spoke Head 1 Radial Spoke Head 3 Radial Spoke Head Outer Dense Fiber Radial Spoke Meiotic Spindle Regulation Of ARF Protein Signal Transduction Establishment Of Epithelial Cell Polarity 9+2 Motile Cilium Phosphatidylinositol-3,4,5-trisphosphate Binding Condensed Nuclear Chromosome Axoneme Assembly
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