WDTC1

Name	WD and tetratricopeptide repeats 1
Structure
Interactors	3 interactors: DDB1 MED23 MED4
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Enzyme Inhibitor Activity Protein Binding Histone Binding Histone Deacetylase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Glucose Metabolic Process Regulation Of Cell Size Protein Ubiquitination Cellular Response To Insulin Stimulus Multicellular Organism Growth Negative Regulation Of Fatty Acid Biosynthetic Process Intracellular Chemical Homeostasis
Pathways	Neddylation
GWAS	No GWAS studies recorded
Entrez ID	23038
HPRD ID	10307
Ensembl ID	ENSG00000142784
Uniprot IDs	Q8N5D0
PDB IDs	3I7N
GO Terms Enriched among Interactors ?	Positive Regulation Of DNA-templated Transcription, Elongation Transcription Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Mediator Complex Core Mediator Complex Positive Regulation Of Transcription Elongation By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Elongation By RNA Polymerase II Regulation Of DNA-templated Transcription Elongation Protein-DNA Complex Assembly Positive Regulation By Virus Of Viral Protein Levels In Host Cell Positive Regulation Of T Cell Extravasation Base-excision Repair, AP Site Formation Via Deaminated Base Removal WD40-repeat Domain Binding Cul4B-RING E3 Ubiquitin Ligase Complex Transcription Coactivator Activity Ubiquitin Ligase Complex Scaffold Activity Nucleic Acid Metabolic Process UV-damage Excision Repair Spindle Assembly Involved In Female Meiosis Cul4A-RING E3 Ubiquitin Ligase Complex Base-excision Repair, AP Site Formation Meiotic Spindle Assembly Cellular Component Assembly Epigenetic Programming In The Zygotic Pronuclei Positive Regulation Of Cellular Extravasation Nuclear Vitamin D Receptor Binding Ectopic Germ Cell Programmed Cell Death Nucleobase-containing Compound Metabolic Process Positive Regulation Of Biosynthetic Process Programmed Cell Death Involved In Cell Development Meiotic Spindle Organization Positive Regulation Of Gluconeogenesis Cullin Family Protein Binding Cul4-RING E3 Ubiquitin Ligase Complex Viral Release From Host Cell Nuclear Thyroid Hormone Receptor Binding Positive Regulation Of Viral Genome Replication Epigenetic Programming Of Gene Expression Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of T Cell Migration Regulation Of Cellular Extravasation Biological Process Involved In Interaction With Symbiont Positive Regulation Of Lymphocyte Migration Nucleobase-containing Compound Biosynthetic Process Positive Regulation Of Glucose Metabolic Process Positive Regulation Of Metabolic Process