ATG7

Name	autophagy related 7
Structure	No pdb structure
Interactors	11 interactors: APP ATG10 ATG12 ATG3 EEF1D GABARAP GABARAPL2 IRF2 MAP1LC3A MAP1LC3B TRIM7
GO Annotations	Cellular Component	Phagophore Assembly Site Extracellular Region Cytoplasm Cytosol Axoneme Secretory Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Ubiquitin-like Modifier Activating Enzyme Activity Atg12 Activating Enzyme Activity Atg8 Activating Enzyme Activity Protein Homodimerization Activity
	Biological Process	Autophagosome Assembly Mitophagy Protein Lipidation Autophagy Cellular Response To Nitrogen Starvation Cellular Response To Starvation Positive Regulation Of Catabolic Process Protein Transport Macroautophagy Positive Regulation Of Protein Modification Process Response To Nutrient Levels Protein Modification By Small Protein Conjugation Cellular Response To Stress Piecemeal Microautophagy Of The Nucleus Regulation Of Circadian Rhythm Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Protein Catabolic Process Rhythmic Process Defense Response To Virus Regulation Of Macromolecule Metabolic Process Cellular Response To Hyperoxia Regulation Of Primary Metabolic Process
Pathways	Macroautophagy Macroautophagy Neutrophil degranulation Signaling by BRAF and RAF1 fusions Antigen processing: Ubiquitination & Proteasome degradation
GWAS	Aspartate aminotransferase levels ( 33547301 ) Body fat mass ( 28552196 ) Body size at age 10 ( 32376654 ) Circulating chemerin levels ( 25521368 ) HDL cholesterol ( 24097068 25961943 ) HDL cholesterol levels ( 28334899 ) Heel bone mineral density ( 28869591 ) Heel bone mineral density x serum urate levels interaction ( 34046847 ) Hip circumference adjusted for BMI ( 34021172 ) Hip index ( 34021172 ) Male-pattern baldness ( 28196072 ) Pulse pressure ( 30578418 ) Relative hand skill in reading disability ( 24068947 ) Small vessel stroke ( 29123153 ) Systolic blood pressure ( 30578418 27618452 27618447 ) Waist-to-hip ratio adjusted for BMI ( 34021172 )
Entrez ID	10533
HPRD ID	12293
Ensembl ID	ENSG00000197548
Uniprot IDs	B3KQM6 O95352
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Autophagy Of Mitochondrion Autophagosome Assembly Autophagosome Organization Macroautophagy Vacuole Organization Cellular Response To Nitrogen Starvation Autophagosome Maturation Phosphatidylethanolamine Binding Autophagosome Membrane Autophagy Mitophagy Autophagosome Protein-containing Complex Disassembly Organelle Assembly Atg12 Transferase Activity Phospholipid Binding Atg8-family Ligase Activity Cellular Response To Starvation Atg12-Atg5-Atg16 Complex Response To Stress Response To Starvation Microtubule Binding Cellular Response To Nutrient Levels Cellular Component Assembly Glycophagy Ubiquitin Protein Ligase Binding Catabolic Process GABA Receptor Binding Response To Lead Ion Ubiquitin-like Protein Transferase Activity Cytosol Glycogen Catabolic Process Cellular Response To Copper Ion Nucleophagy Protein-containing Complex Organization Cytoplasmic Vesicle Polysaccharide Catabolic Process Cellular Response To Stress Response To Nutrient Levels Response To Copper Ion Organelle Organization Beta-tubulin Binding Organelle Membrane Endomembrane System Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Atg8-family Conjugating Enzyme Activity