APP - Wiki-MPM

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
TPD52L2	TPD52 like 2		Phenethyl Isothiocyanate
TPD52L3	TPD52 like 3
TPH1	tryptophan hydroxylase 1	Serotonin and melatonin biosynthesis NGF-stimulated transcription	Sapropterin LX1031 Telotristat ethyl
TPI1	triosephosphate isomerase 1	Glycolysis Gluconeogenesis	Zinc N-Hydroxy-4-phosphonobutanamide 2-Phosphoglycolic Acid Phosphoglycolohydroxamic Acid 3-(2-Benzothiazolylthio)-1-Propanesulfonic Acid [2(Formyl-Hydroxy-Amino)-Ethyl]-Phosphonic Acid 5-fluorotryptophan 2-Carboxyethylphosphonic Acid tert-butanol Dihydroxyacetone phosphate 1,4-Dithiothreitol 3-phospho-D-glyceric acid 3-(BUTYLSULPHONYL)-PROPANOIC ACID Artenimol Zinc acetate Zinc chloride Zinc sulfate, unspecified form	Anemia due to disorders of glycolytic enzymes, including: Hexokinase (HK) deficiency; Phosphoglycerate kinase 1 (PGK1) deficiency; Triose-phosphate isomerase (TPI) deficiency; Glucose phosphate isomerase (GPI) deficiency; Bisphosphoglycerate mutase (BPGM) deficiency
TPMT	thiopurine S-methyltransferase	Methylation Defective TPMT causes TPMT deficiency Azathioprine ADME	Olsalazine	Thiopurine S-methyltransferase deficiency (TPMT deficiency)
TPPP	tubulin polymerization promoting protein
TPRA1	transmembrane protein adipocyte associated 1
TPRXL	tetrapeptide repeat homeobox like (pseudogene)
TPT1	tumor protein, translationally-controlled 1		Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
TRAF3IP1	TRAF3 interacting protein 1	Intraflagellar transport Intraflagellar transport
TRAF6	TNF receptor associated factor 6	PIP3 activates AKT signaling MyD88:MAL(TIRAP) cascade initiated on plasma membrane NOD1/2 Signaling Pathway TICAM1, RIP1-mediated IKK complex recruitment Regulated proteolysis of p75NTR Downstream TCR signaling NRIF signals cell death from the nucleus NRIF signals cell death from the nucleus p75NTR recruits signalling complexes NF-kB is activated and signals survival FCERI mediated NF-kB activation TAK1-dependent IKK and NF-kappa-B activation activated TAK1 mediates p38 MAPK activation JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 CLEC7A (Dectin-1) signaling Ub-specific processing proteases Ovarian tumor domain proteases PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling TICAM1,TRAF6-dependent induction of TAK1 complex Interleukin-1 signaling TRAF6 mediated IRF7 activation TRAF6 mediated NF-kB activation TRAF6 mediated NF-kB activation IRAK1 recruits IKK complex IKK complex recruitment mediated by RIP1 IRAK2 mediated activation of TAK1 complex TRAF6-mediated induction of TAK1 complex within TLR4 complex Alpha-protein kinase 1 signaling pathway SARS-CoV-1 activates/modulates innate immune responses SARS-CoV-2 activates/modulates innate and adaptive immune responses TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation MyD88 dependent cascade initiated on endosome IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation Regulation of NF-kappa B signaling MyD88 cascade initiated on plasma membrane
TRAIP	TRAF interacting protein	Antigen processing: Ubiquitination & Proteasome degradation
TRAM1	translocation associated membrane protein 1	SRP-dependent cotranslational protein targeting to membrane
TRAP1	TNF receptor associated protein 1	Respiratory electron transport Citric acid cycle (TCA cycle)
TRAPPC2L	trafficking protein particle complex subunit 2L	COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
TRAPPC3	trafficking protein particle complex subunit 3	COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs	Palmitic Acid Myristic acid S-palmitoyl-L-cysteine
TRAPPC4	trafficking protein particle complex subunit 4	COPII-mediated vesicle transport Syndecan interactions RAB GEFs exchange GTP for GDP on RABs	S-palmitoyl-L-cysteine
TRAPPC9	trafficking protein particle complex subunit 9	COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs		Nonsyndromic autosomal recessive mental retardation (NS-ARMR)
TRDMT1	tRNA aspartic acid methyltransferase 1	tRNA modification in the nucleus and cytosol	Pentamidine S-adenosyl-L-homocysteine Glycerin
TRIB2	tribbles pseudokinase 2

Search Results for: APP