Search Results for: APP

2116 interactions involving APP - amyloid beta precursor protein found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
TMEM97 transmembrane protein 97
TMOD2 tropomodulin 2
  • Striated Muscle Contraction
TMOD4 tropomodulin 4
  • Striated Muscle Contraction
TMUB1 transmembrane and ubiquitin like domain containing 1
TMX3 thioredoxin related transmembrane protein 3
  • Platelet degranulation
TNFAIP8L1 TNF alpha induced protein 8 like 1
  • PI Metabolism
TNFRSF14 TNF receptor superfamily member 14
  • TNFs bind their physiological receptors
  • Co-inhibition by BTLA
  • Co-inhibition by BTLA
TNFSF13B TNF superfamily member 13b
  • TNFR2 non-canonical NF-kB pathway
  • TNFs bind their physiological receptors
  • TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
  • 1,4-Dioxane
  • Belimumab
TNFSF14 TNF superfamily member 14
  • TNFR2 non-canonical NF-kB pathway
  • TNFs bind their physiological receptors
  • TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
  • TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
TNIP2 TNFAIP3 interacting protein 2
  • MAP3K8 (TPL2)-dependent MAPK1/3 activation
  • Ovarian tumor domain proteases
TNNT2 troponin T2, cardiac type
  • Striated Muscle Contraction
  • Dilated cardiomyopathy (DCM)
  • Hypertrophic cardiomyopathy (HCM)
TOB1 transducer of ERBB2, 1
TOM1 target of myb1 membrane trafficking protein
  • Neutrophil degranulation
TOM1L2 target of myb1 like 2 membrane trafficking protein
TOMM5 translocase of outer mitochondrial membrane 5
  • Mitochondrial protein import
  • PINK1-PRKN Mediated Mitophagy
TOP1 DNA topoisomerase I
  • SUMOylation of DNA replication proteins
  • Irinotecan
  • Dactinomycin
  • Doxorubicin
  • Topotecan
  • Camptothecin
  • Edotecarin
  • Lucanthone
  • Elsamitrucin
  • 7-ethyl-10-hydroxycamptothecin
  • Sodium stibogluconate
  • Cositecan
  • XMT-1001
  • Rubitecan
  • 2,3-DIMETHOXY-12H-[1,3]DIOXOLO[5,6]INDENO[1,2-C]ISOQUINOLIN-6-IUM
  • 4-(5,11-DIOXO-5H-INDENO[1,2-C]ISOQUINOLIN-6(11H)-YL)BUTANOATE
  • Hexylresorcinol
  • Sacituzumab govitecan
  • Trastuzumab deruxtecan
TOX2 TOX high mobility group box family member 2
TP53BP2 tumor protein p53 binding protein 2
  • Activation of PUMA and translocation to mitochondria
  • TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
  • TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
  • TP53 Regulates Transcription of Death Receptors and Ligands
  • Regulation of TP53 Activity through Association with Co-factors
TP53TG1 TP53 target 1
TP53TG5 TP53 target 5

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