Search Results for: APP

2116 interactions involving APP - amyloid beta precursor protein found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
TET3 tet methylcytosine dioxygenase 3
  • TET1,2,3 and TDG demethylate DNA
  • Chromatin modifications during the maternal to zygotic transition (MZT)
TEX2 testis expressed 2
  • RHOA GTPase cycle
TEX44 testis expressed 44
TEX56P testis expressed 56, pseudogene
TFPI tissue factor pathway inhibitor
  • Extrinsic Pathway of Fibrin Clot Formation
  • IIa Recombinant Human
  • Dalteparin
  • Andexanet alfa
TFPT TCF3 fusion partner
  • UCH proteinases
  • DNA Damage Recognition in GG-NER
TGFB1 transforming growth factor beta 1
  • Platelet degranulation
  • Influenza Virus Induced Apoptosis
  • Cell surface interactions at the vascular wall
  • Molecules associated with elastic fibres
  • Downregulation of TGF-beta receptor signaling
  • Downregulation of TGF-beta receptor signaling
  • TGF-beta receptor signaling activates SMADs
  • TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
  • TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
  • Syndecan interactions
  • ECM proteoglycans
  • SMAD2/3 Phosphorylation Motif Mutants in Cancer
  • TGFBR2 MSI Frameshift Mutants in Cancer
  • TGFBR2 Kinase Domain Mutants in Cancer
  • TGFBR1 KD Mutants in Cancer
  • TGFBR1 LBD Mutants in Cancer
  • Transcriptional regulation of white adipocyte differentiation
  • UCH proteinases
  • Interleukin-4 and Interleukin-13 signaling
  • RUNX3 regulates CDKN1A transcription
  • Regulation of RUNX3 expression and activity
  • RUNX3 regulates p14-ARF
  • TGFBR3 regulates TGF-beta signaling
  • Hyaluronidase (ovine)
  • Terazosin
  • Hyaluronidase (human recombinant)
  • Foreskin fibroblast (neonatal)
  • Foreskin keratinocyte (neonatal)
  • Hyaluronidase
  • Graft-versus-host disease
  • Allograft rejection
  • Camurati-Engelmann disease; Progressive diaphyseal dysplasia
TGFB2 transforming growth factor beta 2
  • Platelet degranulation
  • Molecules associated with elastic fibres
  • TGF-beta receptor signaling activates SMADs
  • ECM proteoglycans
  • TGFBR3 regulates TGF-beta signaling
  • Trabedersen
  • Graft-versus-host disease
  • Allograft rejection
TGFBR2 transforming growth factor beta receptor 2
  • Downregulation of TGF-beta receptor signaling
  • Downregulation of TGF-beta receptor signaling
  • TGF-beta receptor signaling activates SMADs
  • TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
  • TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
  • SMAD2/3 Phosphorylation Motif Mutants in Cancer
  • TGFBR2 MSI Frameshift Mutants in Cancer
  • TGFBR2 Kinase Domain Mutants in Cancer
  • TGFBR1 KD Mutants in Cancer
  • TGFBR1 LBD Mutants in Cancer
  • UCH proteinases
  • TGFBR3 regulates TGF-beta signaling
  • Foreskin fibroblast (neonatal)
  • Foreskin keratinocyte (neonatal)
  • Fostamatinib
  • Loeys-Dietz syndrome (LDS)
  • Colorectal cancer
  • Familial thoracic aortic aneurysm and dissection (TAAD); Aortic aneurysm familial thoracic type (AAT)
TGIF1 TGFB induced factor homeobox 1
  • Downregulation of SMAD2/3:SMAD4 transcriptional activity
  • SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
  • Holoprosencephaly (HPE)
TGM2 transglutaminase 2
  • Guanosine-5'-Diphosphate
  • Hexylresorcinol
THAP1 THAP domain containing 1
  • Primary torsion dystonia (PTD)
THAP3 THAP domain containing 3
THAP4 THAP domain containing 4
THAP7 THAP domain containing 7
THBS1 thrombospondin 1
  • Platelet degranulation
  • Signaling by PDGF
  • Integrin cell surface interactions
  • Syndecan interactions
  • Defective B3GALTL causes PpS
  • O-glycosylation of TSR domain-containing proteins
  • RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
THBS4 thrombospondin 4
  • Signaling by PDGF
TICRR TOPBP1 interacting checkpoint and replication regulator
  • Cyclin A/B1/B2 associated events during G2/M transition
TIGAR TP53 induced glycolysis regulatory phosphatase
  • TP53 Regulates Metabolic Genes
TIGD1 tigger transposable element derived 1

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